26040-62-0

Usage

Uses

Used in Food Industry:
Methyl 7-chloroheptanoate is used as a flavoring agent for adding a fruity note to various food products.
Used in Perfume and Personal Care Products:
Methyl 7-chloroheptanoate is used as a fragrance ingredient in perfumes and personal care products, enhancing their scent profiles.
Used in Pharmaceutical Industry:
Methyl 7-chloroheptanoate has potential applications in the pharmaceutical industry, although specific uses are not detailed in the provided materials.
Used in Agrochemical Industry:
Methyl 7-chloroheptanoate also has potential applications in the agrochemical industry, but the exact uses are not specified in the provided materials.

Upstream product

• 67-56-1 methanol 
• 821-57-8 7-chloroheptanoic acid 
• 186581-53-3 diazomethane 
• 201230-82-2 carbon monoxide 
• 502-42-1 cycloheptanone 

Downstream Products

• 31642-84-9 6-Phenylheptansaeuremethylester 
• 31642-83-8 5-Phenylheptansaeuremethylester 
• 101689-18-3 7-phenylheptanoic acid methyl ester 
• 506-13-8 16-hydroxyhexadecanoic acid 
• 112-63-0 Methyl linoleate 
• 60-33-3 linoleic acid 

Relevant academic research and scientific papers

Palladium(II)-catalyzed oxidation of aldehydes and ketones. 1. Carbonylation of ketones with carbon monoxide catalyzed by palladium(II) chloride in methanol

Unsubstituted or alkyl-substituted cyclic ketones react with PdCl2 in methanol under a CO atmosphere to give mainly acyclic diesters along with some acyclic chloro-substituted monoesters. The monosubstituted cyclic ketones, 2-hydroxy- and 2-methoxycyclohexanone, do not give ring cleavage but rather produce 2-(carbomethoxy)cyclohex-2-en-1-one. 13CO labeling experiments indicate one CO is inserted in forming the diester product so the second ester group must arise from the original ketone group. Two mechanisms are possible for the diester reaction. One involves initial Pd(II)-CO2CH3 insertion across the double bond of the enol form of the ketone while the second involves initial addition of Pd(II)-OCH3 followed by CO insertion into the new Pd(II) carbon bond formed. Pd(II) elimination and acid-catalyzed ring cleavage produce the second methyl ester group in both routes. The chloro-substituted monoester is formed by initial Pd(II)-Cl insertion across the double bond followed by the acid-catalyzed ring cleavage. The 2-(carbomethoxy)cyclohex-2-en-1-one must result from elimination of water or methanol from the α-ketoester product formed by the initial methoxycarbonylation of the enol form of the ketone. As expected, the acyclic ketone 2-decanone, formed methyl acetate and a mixture of methyl nonanoate and products.

Palladium(II) catalyzed carbonylation of ketones

Cyclic ketones react with PdCl2 in methanol under a CO atmosphere to give mainly diesters by a ring cleavage reaction along with some chloro- substituted monoester, 13CO labeling experiments indicate the major product is formed by a mechanism involving Pd(II)-CO2CH3 insertion across the double bond of the enol form of the ketone. Pd(II) elimination and acid- catalyzed ring cleavage form a second methyl ester group. (C) 2000 Elsevier Science Ltd.

A New Oxaanalog of Myristic Acid that Suppresses Replication of Human Immunodeficiency Virus

A series of oxaanalogs of myristic acid were synthesized and tested for antiviral activity in MT4 cells infected with human immunodeficiency virus 1 (HIV-1).The synthesized acids have no toxic effect on uninfected MT4 cells at a concentration of 100μM. 14,14,14-Trifluoro-12-oxatetradecanoic acid substantially (by 75percent) inhibits the reproduction of HIV-1.Other compounds synthesized, (7Z)-13-, (9Z)-13-, and (7Z)-11-oxatetradecenoic acids, exhibit no antiviral effect.Key words: inhibitors of retroviruses; anti-HIV agents; protein N-myristoylation; mystoylCoA: protein-N-myristoyltransferase; myristic acid; oxaanalogs; inhibitors of virus-specific protein myristoylation