260418-25-5Relevant academic research and scientific papers
SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES
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Page/Page column 206; 207, (2016/10/31)
Site-specific antibody-drug conjugates are described, in particular conjugates comprising an antibody which binds PSMA, and which comprises an amino acid substitution of an interchain cysteine residue by an amino acid that is not cysteine and pyrrolobenzo
SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES
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Page/Page column 209; 210, (2016/10/31)
Site-specific antibody-drug conjugates are described, in particular conjugates comprising an antibody, which binds MUC1 and comprises an amino acid substitution of an interchain cysteine residue by an amino acid that is not cysteine, and pyrrolobenzodiaze
SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES
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, (2016/10/31)
Site-specific antibody-drug conjugates are described, in particular conjugates comprising an antibody that binds CD19 and which comprises an amino acid substitution of an interchain cysteine residue by an amino acid that is not cysteine, and pyrrolobenzod
SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES
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, (2016/10/31)
Site-specific antibody-drug conjugates are described, in particular conjugates comprising an antibody, which binds CD25 and comprises an amino acid substitution of an interchain cysteine residue by an amino acid that is not cysteine, and pyrrolobenzodiaze
SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES
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, (2016/11/02)
Site-specific antibody-drug conjugates are described, in particular conjugates comprising pyrrolobenzodiazepines (PBDs) having a labile protecting group in the form of a linker. The site of conjugation, along with modification of the antiobody moiety, all
SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES
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, (2016/11/02)
Site-specific antibody-drug conjugates are described, in particular conjugates comprising an antibody, which binds HER2 and comprises an amino acid substitution of an interchain cysteine residue by an amino acid that is not cysteine, and pyrrolobenzodiaze
SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES
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, (2016/10/31)
Site-specific antibody-drug conjugates are described, in particular conjugates comprising pyrrolobenzodiazepines (PBDs) having a labile protecting group in the form of a linker. The site of conjugation, along with modification of the antiobody moiety, all
PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF
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Page/Page column 129; 130, (2015/04/28)
RJW/FP7067259 150 ABSTRACT A compound which is selected from A: A O OO O O O I O NH O O O O O O O O N H N H N H OO OH H O N N OO H N N B: 5 B O OO O O O Br O NH O O O O O O O O N H N H N H OO OH H O N N OO H N N; and C C O O N H N H O N H OO OO O O N O OO
HUMANIZED ANTI-TN-MUC1 ANTIBODIES AND THEIR CONJUGATES
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Page/Page column 213; 214, (2015/11/09)
Humanized anti-Tn-MUC1 antibodies and conjugates thereof. Conjugates comprising pyrrolobenzodiazepines (PBDs) having a labile protecting group in the form of a linker to the antibody are described.
PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES
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, (2015/04/28)
Conjugates of specific PBD dimers with an antibody that binds to CD22, the antibody comprising a VH domain having the sequence according to SEQ ID NO. 1.
