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Thiocyanic acid, 2-fluorophenyl ester, also known as 2-fluorophenyl thiocyanate, is an organic compound with the chemical formula C7H5FNS. It is a colorless to pale yellow liquid that is soluble in organic solvents. Thiocyanic acid, 2-fluorophenyl ester is formed by the esterification of thiocyanic acid with 2-fluorophenol, where the hydroxyl group of the phenol is replaced by the thiocyanate group. It is used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. Due to its reactivity, it is important to handle Thiocyanic acid, 2-fluorophenyl ester with care, as it can be toxic and may cause irritation to the skin, eyes, and respiratory system.

2605-31-4

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2605-31-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2605-31-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,0 and 5 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2605-31:
(6*2)+(5*6)+(4*0)+(3*5)+(2*3)+(1*1)=64
64 % 10 = 4
So 2605-31-4 is a valid CAS Registry Number.

2605-31-4Downstream Products

2605-31-4Relevant academic research and scientific papers

Nitromethane as a cyanating reagent for the synthesis of thiocyanates

Wang, Zuo-Hui,Ji, Xiao-Ming,Hu, Mao-Lin,Tang, Ri-Yuan

supporting information, p. 5067 - 5070 (2015/08/06)

Nitromethane has been developed to be an effective cyanating reagent for the synthesis of thiocyanates. In the presence of iodine and base, a wide range of disulfides were reacted with nitromethane smoothly to give diverse thiocyanates in moderate to good yields.

Transition-metal-free cross-coupling of thioethers with aryl(cyano)iodonium triflates: A facile and efficient method for the one-pot synthesis of thiocyanates

Zhu, Dan,Chang, Denghu,Shi, Lei

supporting information, p. 7180 - 7183 (2015/04/27)

A novel transition-metal-free cross-coupling method for the one-step synthesis of thiocyanates via the C-S bond cleavage of readily available thioethers with aryl(cyano)-iodonium triflates as the cyanating agent is developed. This process features relatively broad substrate scopes, less-toxic hypervalent iodine reagents, mild operating conditions, excellent functional group compatibilities, and affords various thiocyanates in moderate to good yields. This journal is

Copper-catalyzed cyanation of disulfides by azobisisobutyronitrile leading to thiocyanates

Teng, Fan,Yu, Jin-Tao,Yang, Haitao,Jiang, Yan,Cheng, Jiang

supporting information, p. 12139 - 12141 (2014/12/11)

The copper-catalyzed cyanation of disulfides by azobisisobutyronitrile (AIBN) was developed, leading to thiocyanates in moderate to good yields. This procedure tolerates a series of functional groups, such as chloro, nitro, methyl and methoxycarbonyl in the phenyl ring of disulfides. Notably, it enables the use of two ArS units in (ArS)2. CuI was found to be essential for the in situ formation of cyanide anions. This journal is

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