26059-94-9Relevant articles and documents
Synthesis of new 1,2,3-triazol-4-yl-quinazoline nucleoside and acyclonucleoside analogues
Ouahrouch, Abdelaaziz,Taourirte, Moha,Engels, Joachim W.,Benjelloun, Soumaya,Lazrek, Hassan B.
, p. 3638 - 3653 (2014/04/17)
In this study, we describe the synthesis of 1,4-disustituted-1,2,3- triazoloquinazoline ribonucleosides or acyclonucleosides by means of 1,3-dipolar cycloaddition between various O or N-Alkylated propargyl-quinazoline and 1'-Azido-2',3',5'-tri-Obenzoylribose or activated alkylating agents under microwave conditions. None of the compounds selected showed significant anti-HCV activity in vitro.
Synthesis and anticonvulsant activity of acetylenic quinazolinone derivatives
Usifoh, Cyril O.,Scriba, Gerhard K. E.
, p. 261 - 266 (2007/10/03)
Acetylenic derivatives of quinazolinones and quinazolinediones were synthesized and evaluated for their anticonvulsant activity. Most compounds displayed seizure-antagonizing activity in the maximal electroshock test (MES test) in most cases associated wi