26060-47-9Relevant academic research and scientific papers
Crystallographic study of restricted rotation in o-formanilides
Boeyens, Jan C. A.,Denner, Louis,Evans, Deborah G.
, p. 175 - 188 (1988)
The crystal structures of cis- and trans-o-methylformanilide, of its cis-thio analogue, and of trans-o-phenylformanilide have been studied with a view to clarifying the anomalously high barrier to rotation of the carbonyl group.The pair of resolved geometrical isomers is shown to be stabilized in the solid state primarily by hydrogen bonding.The increased barrier to rotation is inferred not to arise from mesomeric involvement of the carbonyl group, but from nuclear screening by the nitrogen lone pair.
Compound comprising urea and thiourea structures and synthesis method and application of compound
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Paragraph 0060-0061, (2019/08/07)
The invention relates to an organic small molecular compound comprising urea and thiourea structures in a formula I and a synthesis method and application of the compound. According to in-vitro antitumor activity tests, the compound has high antitumor act
A new convenient synthesis of 5-aryl-2-(arylamino)-1,3,4-oxadiazole derivatives
Kumar, Sanjeev
body text, p. 216 - 220 (2012/08/29)
Electrical energy offers numerous benefits for conducting a synthesis, including increased reaction rates, yield enhancements and cleaner chemistries. 5-Aryl-2-(arylamino)-1,3,4-oxadiazoles were synthesized directly from acylthiosemicarbazide on the plati
Synthesis of O-ethyl thioformate: A useful reagent for the thioformylation of amines
Borths, Christopher J.,Chan, Johann,Burke, Brenda J.,Larsen, Robert D.
experimental part, p. 3139 - 3142 (2010/03/24)
O-Ethyl thioformate has been synthesized from triethylorthoformate and hydrogen sulfide gas using a Bronstead acid catalyst. The product can be isolated as a neat liquid in 83% overall yield. Both the crude and purified thiolate can be used to thioformylate a variety of amines in good to excellent yields.
