2610-95-9Relevant articles and documents
Aromatic ring synthesis by 1,3-Michael-Claisen annulation: Application to a Trolox analogue and to Precocene II
Solladie,Boeffel,Maignan
, p. 2065 - 2074 (1996)
A Trolox analogue, 3,4-dihydro-2-ethoxycarbonyl-6-methoxy-7-hydroxybenzopyran and Precocene II, were prepared from substituted α-methylene-δ-valerolactone and 1,1-bis-(methylthio)-2-propanone or butanone, via a 1,3-Michael-Claisen annulation.
Synthesis of the ester side chains of homoharringtonine and harringtonine using lactones as building blocks
Dang, Fang-Fang,Wang, Cui-Cui,Han, Feng,Zhang, Zhi-Wei
supporting information, p. 317 - 323 (2020/10/14)
The efficient synthesis of the ester side chains of homoharringtonine and harringtonine using lactones as building blocks has been developed. The synthesis used classic reactions from readily available starting materials. Reactions of the lactone bearing
Calcium(II)- And Triflimide-Catalyzed Intramolecular Hydroacyloxylation of Unactivated Alkenes in Hexafluoroisopropanol
Qi, Chenxiao,Yang, Shengwen,Gandon, Vincent,Leb?uf, David
supporting information, p. 7405 - 7409 (2019/10/02)
We report an efficient intramolecular hydroacyloxylation of unactivated alkenes, offering a streamlined access to relevant γ-lactones, which features the utilization of either a calcium(II) salt or triflimide as a catalyst in hexafluoroisopropanol. This method could be applied to the synthesis of natural products and the late-stage functionalization of natural and bioactive molecules. Additionally, DFT computations were used to elucidate the twist of reactivity observed between the hydroamidation and hydroacyloxylation of unactivated alkenes regarding the formation of 5- and 6-membered rings.
Formation of δ-Lactones with anti-Baeyer–Villiger Regiochemistry: Investigations into the Mechanism of the Cerium-Catalyzed Aerobic Coupling of β-Oxoesters with Enol Acetates
Geibel, Irina,Dierks, Anna,Müller, Thomas,Christoffers, Jens
, p. 7245 - 7254 (2017/05/31)
The cerium-catalyzed, aerobic coupling of β-oxoesters with enol acetates and dioxygen yields δ-lactones with a 1,4-diketone moiety. In contrast to the Baeyer–Villiger oxidation (BVO), where the higher substituted residue migrates; in the case of this oxid