26104-01-8Relevant academic research and scientific papers
Divergent Total Syntheses of Rhodomyrtosones A and B
Gervais, Anais,Lazarski, Kiel E.,Porco, John A.
, p. 9584 - 9591 (2015/10/12)
Herein, we report total syntheses of the tetramethyldihydroxanthene natural product rhodomyrtosone B and the related bis-furan β-triketone natural product rhodomyrtosone A. Nickel-(II)-catalyzed 1,4-conjugate addition of an α-alkylidene-β-dicarbonyl subst
Antifungal Activities of 2,4,6-Trihydroxyacylophenones and Related Compounds
Mizobuchi, Shigeyuki,Sato, Yuko
, p. 719 - 724 (2007/10/02)
The antifungal activities of sixty two 2,4,6-trihydroxyacylophenones and related compounds against Trichophyton spp. and other fungi were investigated to study their structure-activity relationship.It was found that the activities of these compounds were closely related to the length of the acyl and alkyl chains attached to the 1,3,5-trihydroxybenzene moiety.Among the compounds tested, 2,4,6-trihydroxy-3-nonylacetophenone (V-7) showed the highest activity against Trichophyton spp., with MICs being 1.57 μg/ml, and was more active than amphotericin B.
The Synthesis of Some Novel Deoxyhumulone Analogues. Observations on the Air-oxidation of 2',4',6'-Trihydroxy-3'-isopentyl-5'-(3-methylbut-2-enyl)isovalerophenone and its corresponding Humulone Derivatives
Cann, Martin R.,Davis, Anne-Marie,Shannon, Patrick V. R.
, p. 1413 - 1421 (2007/10/02)
Two novel analogues of natural deoxyhumulone have been synthesised: (a) with the 3-methylbutanoyl side chain replaced by benzoyl, and (b) with the dimethylallyl substituents replaced by the cycloheptylidene analogues.Oxidation of these with air gave the c
