261364-41-4

Upstream product

• 95-87-4 2,5-Dimethylphenol 
• 40662-15-5 4,4,5,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-one 
• 924-50-5 Methyl 3,3-dimethylacrylate 
• 92617-58-8 3-(2'-hydroxy-3',6'-dimethylphenyl)-3,3-dimethylpropanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 261364-42-5 1-O-(tert-butyldimethylsilyl)-3-(2'-Boc-alaninyl-3',6'-dimethylphenyl)-3,3-dimethylpropanol 
• 261364-52-7 3-(2'-Boc-β-alaninyl-3',6'-dimethylphenyl)-3,3-dimethylpropionic acid 
• 229958-32-1 3-(2'-Boc-alaninyl-3',6'-dimethylphenyl)-3,3-dimethylpropionic acid 
• 261364-46-9 3-(2'-Boc-β-alaninyl-3',6'-dimethylphenyl)-3,3-dimethylpropanol 
• 261364-45-8 3-(2'-Boc-alaninyl-3',6'-dimethylphenyl)-3,3-dimethylpropanol 
• 261364-50-5 3-(2'-Boc-β-alaninyl-3',6'-dimethylphenyl)-3,3-dimethylpropanal 
• 261364-49-2 3-(2'-Boc-alaninyl-3',6'-dimethylphenyl)-3,3-dimethylpropanal 
• 261364-43-6 1-O-(tert-butyldimethylsilyl)-3-(2'-Boc-β-alaninyl-3',6'-dimethylphenyl)-3,3-dimethylpropanol 

Relevant academic research and scientific papers

A prodrug compound, a prodrug-oligonucleotide synthesis reagents, and manufacture of oligonucleotide-prodrug compounds

PROBLEM TO BE SOLVED: To provide a new prodrug compound where a protective group capable of leaving in a cell is added to an OH group or an SH group of a phosphate group included in a synthetic oligonucleotide which may be a phosphorothioate-type analog o

Drug delivery systems based on trimethyl lock lactonization: Poly(ethylene glycol) prodrugs of amino-containing compounds

A novel methodology for the synthesis of poly(ethylene glycol) (PEG) prodrugs of amino-containing compounds has been developed which is based on the trimethyl lock lactonization reaction. These PEG-modified double prodrugs are water soluble, and by select