26137-10-0

Usage

Uses

Used in Pharmaceutical Synthesis:
(3-bromothiophen-2-yl)(phenyl)methanone is used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique chemical structure allows for the creation of a wide range of medicinal agents.
Used in Organic Electronics:
(3-bromothiophen-2-yl)(phenyl)methanone is used as a component in the field of organic electronics due to its specific chemical structure and properties. It may contribute to the development of novel electronic devices and materials.
Used in Materials Science:
In materials science, (3-bromothiophen-2-yl)(phenyl)methanone is used as a building block for the development of new materials with tailored electronic, optical, or biological properties. Its unique structure can lead to innovative applications in this field.
Used in Research and Development:
(3-bromothiophen-2-yl)(phenyl)methanone is also utilized in research and development for exploring its potential in creating new compounds and materials with specific applications in various industries.

Upstream product

• 672325-70-1 (3-bromothiophen-2-yl)zinc(II) bromide 
• 98-88-4 benzoyl chloride 
• 872-31-1 3-Bromothiophene 
• 6919-61-5 N-methoxy-N-methylbenzamide 
• 100-58-3 phenylmagnesium bromide 
• 930-96-1 3-bromo-2-thiophenecarboxaldehyde 
• 26137-09-7 2-(α-hydroxybenzyl)-3-bromothiophene 

Downstream Products

• 271782-85-5 C₅H₅FeC₅H₄C₄H₂(COC₆H₅)S 
• 1433030-57-9 2-(2-benzoylthiophen-3-yl)benzaldehyde 

Relevant academic research and scientific papers

Palladium(II)-catalyzed Intermolecular Cascade Cyclization of Methylenecyclopropanes with Aromatic Alkynes: Construction of Spirocyclic Compounds Containing Indene and 1,2-Dihydronaphthalene Moieties

A palladium(II)-catalyzed intermolecular cascade cyclization of methylenecyclopropanes with aromatic alkynes is reported in this paper. The reaction involves a migratory insertion of alkyne, an intramolecular Heck-type reaction, and β-H elimination, providing a series of spirocyclic compounds containing indene and 1,2-dihydronaphthalene moieties in moderate to excellent yields upon heating.

Directed metalation and regioselective functionalization of 3-bromofuran and related heterocycles with NaHMDS

A mild and regioselective functionalization protocol for 3-bromofuran and analogs has been developed. Selective metalation and functionalization of C2 can be achieved as a result of the directing effect of the adjacent electron-withdrawing bromo group. In addition, the C5 position can also be selectively functionalized by blocking the C2 position via silylation or by simply controlling the reaction temperature. These functionalized compounds bearing a C3 bromo substituent may be further elaborated by utilizing a Suzuki-Miyaura cross-coupling procedure.

Preparation of aryl ketones via Ni-catalyzed Negishi-coupling reactions with acid chlorides

A Ni-catalyst-catalyzed cross-coupling reaction of organozinc reagents with acid chlorides has been successfully developed. Mild reaction conditions were required to complete the coupling reactions affording the corresponding aryl ketones in good to excellent yields.