26137-48-4

Upstream product

• 518-34-3 Tetrandrin 
• 477-57-6 pheanthine 
• 23495-76-3 1-(3-benzyloxy-4-methoxy-benzyl)-8-bromo-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinoline 
• 121-33-5 vanillin 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 63909-38-6 3-methoxy-4-benzyloxy-ω-nitrostyrolene 
• 22231-61-4 2-[4-(benzyloxy)-3-methoxyphenyl]ethylamine 
• 6948-30-7 5-bromoveratralaldehyde 
• 54291-90-6 5-bromo-3,4-dimethoxy-1-(2-nitrovinyl)benzene 
• 56139-04-9 2-(3-bromo-4,5-dimethoxyphenyl)ethanamine 
• 1131-94-8 homoisovanillic acid 
• 38849-59-1 5-(8-bromo-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-2-methoxy-phenol 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 186581-53-3 diazomethane 

Downstream Products

• 477-57-6 tetrandrine 
• 5096-70-8 (-)-(R)-(N)-methylcoclaurine 
• 58169-28-1 secophaeanthine 
• 115439-17-3 pycmanilline 
• 5701-00-8 (R)-O-methylarmepavine 
• 3423-05-0 (R)-7-methoxy-1-(4-methoxy-benzyl)-2-methyl-1,2,3,4-tetrahydro-isoquinolin-6-ol 
• 3423-07-2 (S)-N-methylcoclaurine 
• 436-77-1 demethyltetrandrine 
• 479-37-8 (+)-obamegine 
• 2107-55-3 (R)-6-ethoxy-7-methoxy-1-(4-methoxy-benzyl)-2-methyl-1,2,3,4-tetrahydro-isoquinoline 

Relevant academic research and scientific papers

ALKALOIDS OF DEHAASIA TRIANDRA

Separation of the basic fraction from Dehaasia triandra afforded two new bisbenzylisoquinoline alkaloids, dehatridine and dehatrine, along with six known alkaloids, isocorydine, corytuberine, atheroline, nantenine, obaberine and a quaternary aporphine alkaloid, xanthoplanine (5). - Keywords: Dehaasia triandra; Lauraceae; Iau-Guoo-Nan; bisbenzylisoquinoline alkaloids; dehatridine; dehatrine.

Full-synthetic method of racemic tetrandrine

The invention discloses a full-synthetic method of racemic tetrandrine, and belongs to the technical field of drug synthesis. The full-synthetic method of the racemic tetrandrine comprises the steps that a synthetic route adopts a convergence synthesis method, a 5-bromovanillin, namely a compound 1 and 3-hydroxy-4-methoxyphenylacetic acid, namely a compound 5 are taken as starting materials to obtain a compound 4 and a compound 6 respectively, then the compound 4 and the compound 6 are taken as raw materials to synthesize a compound 11, a compound 19 is synthesized from the compound 11, and finally, the compound 11 reacts with the compound 19. The full-synthetic method of the racemic tetrandrine has the advantages that the synthetic efficiency is higher, the yield is higher, and the cost is lower; the reaction conditions are milder, the operation is simple and convenient, the industrial value is higher, and a reference is provided for the full-synthetic method of optical voidness tetrandrine.

Alcaloides bisbenzylisoquinoleiques de Albertisia cf. A. papuana

Four new bisbenzylisoquinoline alkaloids were obtained from Albertisia cf.A. papuana Becc. (Menispermaceae).These are (-)-2,2'-bisnorphaeanthine (5), (+)-pangkoramine (7), (+)-pangkorimine (9), and (+)-2'-norcocsuline (14).They are accompanied by the known (+)-daphnoline (2), which is the main alkaloid, and by seven known dimers with one, two, or three ether bridges