26152-02-3

Basic information

• Product Name: (3-CHLORO-PHENYL)-OXO-ACETONITRILE
• Synonyms: 3-CHLOROBENZOYL CYANIDE;(3-CHLORO-PHENYL)-OXO-ACETONITRILE;Benzeneacetonitrile, 3-chloro-a-oxo-
• CAS NO: 26152-02-3
• Molecular Formula: C₈H₄ClNO
• Molecular Weight: 165.58
• Mol File: 26152-02-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 259.774ºC at 760 mmHg
• Flash Point: 110.908 ºC
• Appearance: /
• Density: 1.311 g/cm³
• CAS DataBase Reference: (3-CHLORO-PHENYL)-OXO-ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: (3-CHLORO-PHENYL)-OXO-ACETONITRILE(26152-02-3)
• EPA Substance Registry System: (3-CHLORO-PHENYL)-OXO-ACETONITRILE(26152-02-3)

Safety Data

• Hazardous Substances Data: 26152-02-3(Hazardous Substances Data)

Usage

General Description

(3-Chloro-phenyl)-oxo-acetonitrile, also known as 3-chlorobenzoylacetonitrile, is a chemical compound with the molecular formula C9H6ClNO. It is a white to yellow crystalline solid that is soluble in organic solvents such as ethanol and ether. (3-Chloro-phenyl)-oxo-acetonitrile is primarily used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is also used as a building block for the production of agrochemicals and fine chemicals. Additionally, it can be utilized in the manufacturing of dyes, pigments, and other specialty chemicals. Overall, (3-Chloro-phenyl)-oxo-acetonitrile is a versatile chemical with various industrial applications.

Upstream product

• 1529-41-5 3-chloro-benzeneacetonitrile 
• 30070-63-4 meta-chlorobenzoic anhydride 
• 7677-24-9 trimethylsilyl cyanide 
• 544-92-3 copper(I) cyanide 
• 618-46-2 m-Chlorobenzoyl chloride 
• 57-12-5 cyanide^(1-) 
• 37156-42-6 4-nitrophenyl 3-chlorobenzoate 
• 37156-55-1 2,4-dinitrophenyl 3-chlorobenzoate 

Downstream Products

• 535-80-8 3-chlorobenzoate 
• 26767-07-7 2-(3-chlorophenyl)-2-oxoacetic acid 

Relevant articles and documents

Synthesis of benzoyl cyanide through aerobic photooxidation of benzyl cyanide using carbon tetrabromide as a catalyst

We developed a synthetic method toward benzoyl cyanide through aerobic photooxidation of benzyl cyanide in the presence of carbon tetrabromide under visible light irradiation with fluorescent lamps.

AgI-PEG400-KI catalyzed environmentally benign synthesis of aroyl cyanides using potassium hexacyanoferrate(II) as the cyanating agent

A practical cyanation of aroyl chlorides with 0.2 equivalent of non-toxic cyanide source, K4[Fe(CN)6], 3 mol% AgI, 4 mol% PEG-400, and 3 mol% KI as the catalyst system is described. The reactions were performed in DMF at room temperature and provided the corresponding aroyl cyanides in 64-89% yield, typically in less than ten hours. Georg Thieme Verlag Stuttgart.

Method for producing optically active mandelic acid derivatives

The present invention provides a method for enzymatically producing optically active mandelic acid derivatives. An optically active mandelic acid derivative (shown as Formula II) is produced by reacting a culture or cell body of a microorganism, or processed products thereof, with a phenylglyoxylic acid derivative, and then recovering the obtained optically active mandelic acid derivative, wherein the microorganism has the ability to stereo-selectively reduce the phenylglyoxylic acid derivative. An optically active mandelic acid obtained according to the present invention is useful as an intermediate for the synthesis of pharmaceuticals and agricultural chemicals.