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Usage

Uses

Used in Pharmaceutical Industry:
(2Z)-4-phenyl-5-(phenylhydrazono)-1,3-thiazol-2(5H)-imine is used as a lead compound for the development of new drugs due to its complex structure and the potential biological activities associated with thiazole and phenylhydrazono groups.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (2Z)-4-phenyl-5-(phenylhydrazono)-1,3-thiazol-2(5H)-imine is utilized for its potential to form coordination complexes with metal ions, which can contribute to the discovery of new pharmaceutical agents with various therapeutic applications.
Further research is essential to fully explore the properties and potential uses of this chemical compound, as its complex structure and the presence of biologically active groups suggest a wide range of possible applications in the development of novel therapeutics.

Upstream product

• 2010-06-2 2-Amino-4-phenylthiazole 
• 62-53-3 aniline 
• 55716-62-6 1-bromo-2-phenylglyoxal 1-phenyhydrazone 
• 17356-08-0 thiourea 
• 100-34-5 benzene diazonium chloride 
• 98-86-2 acetophenone 

Downstream Products

• 93546-56-6 N-{Imino-[3-(4-phenyl-5-phenylazo-thiazol-2-yl)-ureido]-methyl}-piperidine-1-carboxamidine 
• 93546-50-0 N-{Imino-[3-(4-phenyl-5-phenylazo-thiazol-2-yl)-ureido]-methyl}-4-methyl-piperazine-1-carboxamidine 
• 1253853-14-3 C₂₁H₁₅N₅OS 
• 1253853-15-4 C₂₁H₁₅N₅OS 
• 1253853-17-6 C₂₂H₁₅IN₄OS 
• 1253853-11-0 C₂₇H₂₀N₄O₂S 
• 1253853-05-2 C₂₃H₁₈N₄OS 
• 1253853-01-8 C₂₂H₁₅ClN₄OS 
• 1253853-16-5 C₂₃H₁₈N₄O₂S 
• 1253853-12-1 C₂₈H₂₀N₄OS 
• 1253853-03-0 C₂₃H₁₈N₄OS 
• 1253853-02-9 C₂₂H₁₄Cl₂N₄OS 
• 1253853-09-6 C₂₂H₁₅BrN₄OS 
• 1253853-10-9 C₂₃H₁₈N₄OS 

Relevant academic research and scientific papers

Potential COVID-19 Drug Candidates Based on Diazinyl-Thiazol-Imine Moieties: Synthesis and Greener Pastures Biological Study

A novel series of 1-aryl-N-[4-phenyl-5-(arylazo)thiazol-2-yl)methanimines has been synthesized via the condensation of 2-amino-4-phenyl-5-arylazothiazole with various aromatic aldehydes. The synthesized imines were characterized by spectroscopic technique

Synthesis and biological evaluation of some substituted amino thiazole derivatives

Condensation of acetophenone with thiourea in presence of halogen (Iodine) gives 2-amino-4-phenylthiazole (I). 2-Amino-4-phenyl-5-phenylazothizole (II) was prepared by coupling of phenyldiazonium chloride with 2-amino-4-phenylthiazole (I). A series of amide can be synthesized by treatment of appropriate substituted acid chlorides (III) with compound (II) using pyridine as solvent. All the synthesized compounds are characterized by the combination of elemental analysis and standard spectroscopic method. They are screened for anti-bacterial activity against Escherichia coli and Staphylococcus aureus as well as screened for antifungal activity against Aspergillus niger and Apergillus oryzae by cup plate method at 1μg/mL concentration in DMF. All the synthesized compounds showed moderate to good microbial activity.