261711-74-4

Basic information

• Product Name: 7-isopropyl-4-methyl-6-thiocyanato-benzothiazol-2-yl-amine
• CAS NO: 261711-74-4
• Molecular Weight: 263.387
• Mol File: 261711-74-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-isopropyl-4-methyl-6-thiocyanato-benzothiazol-2-yl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-isopropyl-4-methyl-6-thiocyanato-benzothiazol-2-yl-amine(261711-74-4)
• EPA Substance Registry System: 7-isopropyl-4-methyl-6-thiocyanato-benzothiazol-2-yl-amine(261711-74-4)

Safety Data

• Hazardous Substances Data: 261711-74-4(Hazardous Substances Data)

Upstream product

• 2051-53-8 5-isopropyl-2-methylphenylamine 
• 540-72-7 sodium thiocyanide 

Downstream Products

• 261709-49-3 toluene-4-thiosulfonic acid S-(2-amino-7-isopropyl-4-methyl-benzothiazol-6-yl)ester 

Relevant articles and documents

Thiocyanation of alkylanilines. A simple and efficient synthesis of thiosulfonates containing 2-aminobenzothiazole

Thiocyanation of anilines was used to introduce a thiol functionality and to construct the aminothiazole ring, all in a single step. A systematic study of thiocyanation of alkyl anilines was investigated to understand the regio-chemistry of the reaction. X-Ray crystal structures of two 2- aminobenzothiazoles were determined to assign the structures without any ambiguity. The intermediates obtained were further expanded to thiosulfonates containing 2-aminobenzothiazoles, which are extremely valuable intermediates to synthesize HIV protease inhibitors. (C) 2000 Elsevier Science Ltd.