261730-55-6

Basic information

• Product Name: 3-AMINO-3-(2-NAPHTHALENYL)-2-PROPENOIC ACID ETHYL ESTER
• Synonyms: 3-AMINO-3-(2-NAPHTHALENYL)-2-PROPENOIC ACID ETHYL ESTER
• CAS NO: 261730-55-6
• Molecular Formula: C15H15NO2
• Molecular Weight: 241.288
• Mol File: 261730-55-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-AMINO-3-(2-NAPHTHALENYL)-2-PROPENOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-3-(2-NAPHTHALENYL)-2-PROPENOIC ACID ETHYL ESTER(261730-55-6)
• EPA Substance Registry System: 3-AMINO-3-(2-NAPHTHALENYL)-2-PROPENOIC ACID ETHYL ESTER(261730-55-6)

Safety Data

• Hazardous Substances Data: 261730-55-6(Hazardous Substances Data)

Upstream product

• 613-46-7 2-naphthalenecarbonitrile 
• 105-36-2 ethyl bromoacetate 
• 62550-65-6 ethyl 2-naphthoylacetate 
• 93-08-3 methyl 2-naphthyl ketone 

Relevant articles and documents

Trifluoroethanol as a Unique Additive for the Chemoselective Electrooxidation of Enamines to Access Unsymmetrically Substituted NH-Pyrroles

An electrochemical method for the synthesis of unsymmetrically substituted NH-pyrroles is described. The synthetic strategy comprises a challenging heterocoupling between two structurally diverse enamines via sequential chemoselective oxidation, addition,

Chiral Lewis Base-Catalyzed, Enantioselective Reduction of Unprotected β-Enamino Esters with Trichlorosilane

Catalytic asymmetric reduction of N-unsubstituted β-enamino esters represents a major challenge for asymmetric catalysis. In this paper, the first organocatalytic system that could be used for the asymmetric hydrosilylation of N-unsubstituted β-enamino esters has been developed. Using N-tert-butylsulfinyl-L-proline-derived amides and L-pipecolinic acid-derived formamides as catalyst, a broad range of β-aryl- and β-alkyl-substituted free β-amino esters could be prepared with high yields and enantioselectivities. The practicality was illustrated by the gram-scale asymmetric synthesis of ethyl (R)-3-amino-3-phenylpropanoate and isopropyl (S)-3-amino-4-(2,3,5-trifluorophenyl)butanoate. The resulting product can be smoothly transformed to the FDA approved medicines dapoxetine and sitagliptin in a short synthetic route.

Reactions of tetrasulfur tetranitride antimony pentachloride complex (S4N4 SbCl5) with primary β-enaminones and β-enamino esters: Synthesis of 4-substituted 3-aroyl-and 3-ethoxycarbonyl-1,2,5-thiadiazoles

The reaction of tetrasulfur tetranitride antimony pentachloride complex (S4N4·SbCl5) with 3-amino-3-alkyl-1-aryl-2-propenones and 3-amino-1,3- diaryl-2-propenones in toluene at 100°C produced 4-substitued 3-aroyl-1,2,5- th