261763-59-1

Basic information

• Product Name: N-{3-[7-(7-acetylamino-5-benzyloxy-1-chloromethyl-1,2-dihydro-benzo[e]indol-3-yl)-7-oxo-heptanoyl]-5-benzyloxy-1-chloromethyl-2,3-dihydro-1H-benzo[e]indol-7-yl}-acetamide
• CAS NO: 261763-59-1
• Molecular Weight: 885.887
• Mol File: 261763-59-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-{3-[7-(7-acetylamino-5-benzyloxy-1-chloromethyl-1,2-dihydro-benzo[e]indol-3-yl)-7-oxo-heptanoyl]-5-benzyloxy-1-chloromethyl-2,3-dihydro-1H-benzo[e]indol-7-yl}-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{3-[7-(7-acetylamino-5-benzyloxy-1-chloromethyl-1,2-dihydro-benzo[e]indol-3-yl)-7-oxo-heptanoyl]-5-benzyloxy-1-chloromethyl-2,3-dihydro-1H-benzo[e]indol-7-yl}-acetamide(261763-59-1)
• EPA Substance Registry System: N-{3-[7-(7-acetylamino-5-benzyloxy-1-chloromethyl-1,2-dihydro-benzo[e]indol-3-yl)-7-oxo-heptanoyl]-5-benzyloxy-1-chloromethyl-2,3-dihydro-1H-benzo[e]indol-7-yl}-acetamide(261763-59-1)

Safety Data

• Hazardous Substances Data: 261763-59-1(Hazardous Substances Data)

Upstream product

• 261763-56-8 7-acetylamino-5-benzyloxy-1-chloromethyl-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester 
• 222835-55-4 N-(tert-butyloxycarbonyl)-N-(3-chloro-2-propen-1-yl)-6-(9-fluorenylmethyloxy-carbonylamino)-4-benzyloxy-1-iodo-2-naphthylamine 
• 222835-56-5 5-(benzyloxy)-3-(tert-butyloxycarbonyl)-1-chloromethyl-7-(9-fluorenylmethyloxy-carbonylamino)-1,2-dihydro-3H-benz[e]indole 
• 286374-31-0 7-amino-5-benzyloxy-1-chloromethyl-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester 
• 142-79-0 pimeloyl chloride 

Relevant articles and documents

Design, synthesis and cytotoxicity evaluation of 1-chloromethyl-5-hydroxy-1,2-dihydro-3H-benz[e]indole (seco-CBI) dimers

Three types of 1-chloromethyl-5-hydroxy-1,2-dihydro-3H-benz[e]indole (seco-CBI) dimers were designed, synthesized and evaluated in vitro by NCI against nine types of cancer cells. Biological results showed that the antitumor activities of these seco-CBI dimers were strongly related to the position and length of the linker and generally with potency increasing in the order of C7-C7 dimers (22i-iv)50 values50 values0.01μM against all the cell lines and showed the highest overall potency of the agents examined (GMG=0.0120μM). Copyright (C) 2000 Elsevier Science Ltd.