2627-77-2

Basic information

• Product Name: 4'-BROMOSALICYLANILIDE
• Synonyms: Salicylanilide,4’-bromo-;4'-BROMO-2-HYDROXYBENZANILIDE;4'-BROMOSALICYLANILIDE;4’-Monobromosalicylanilide;Benzamide,N-(4-bromophenyl)-2-hydroxy-;bromosalicylanilide;N-(4-Bromo-phenyl)-2-hydroxy-benzamide
• CAS NO: 2627-77-2
• Molecular Formula: C₁₃H₁₀BrNO₂
• Molecular Weight: 292.13
• Mol File: 2627-77-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 172 °C
• Boiling Point: 338.3°Cat760mmHg
• Flash Point: 158.4°C
• Appearance: /
• Density: 1.597g/cm³
• PKA: 8.27±0.30(Predicted)
• CAS DataBase Reference: 4'-BROMOSALICYLANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-BROMOSALICYLANILIDE(2627-77-2)
• EPA Substance Registry System: 4'-BROMOSALICYLANILIDE(2627-77-2)

Safety Data

• Hazardous Substances Data: 2627-77-2(Hazardous Substances Data)

Usage

General Description

4’-Bromosalicylanilide is a chemical compound that is commonly used as an intermediate in the synthesis of pharmaceuticals and dyes. It is an organic compound with the molecular formula C13H10BrNO2 and a molecular weight of 288.13 g/mol. 4'-BROMOSALICYLANILIDE contains a bromine atom, a salicyl group, and an anilide group, and is often utilized as a building block in the manufacturing of various drugs and pigments. In addition, 4’-Bromosalicylanilide has been studied for its potential biological activities, including its anti-inflammatory and antimicrobial properties, making it a valuable compound in the field of medicinal chemistry. Overall, this chemical is a versatile component in the production of various pharmaceutical and industrial products.

Upstream product

• 106-40-1 4-bromo-aniline 
• 69-72-7 salicylic acid 
• 1441-87-8 salicyloyl chloride 

Downstream Products

• 13563-07-0 3-(4-Bromophenyl)-2H-1,3-benzoxazine-2,4(3H)-dione 
• 1369423-70-0 11-(4-bromophenyl)-3-(tetrahydro-2H-pyran-2-yl)benzo[f]pyridazino[4,5-b][1,4]oxazepine-4,10(3H,11H)-dione 
• 1321192-29-3 10-(4-bromophenyl)-7-nitrodibenzo[ b,f][1,4]oxazepin-11-(10H)-one 
• 28534-34-1 3-(4-bromo-phenyl)-2-methoxycarbonylmethyl-4-oxo-3,4-dihydro-2H-benzo[e][1,3]oxazine-2-carboxylic acid methyl ester 

Relevant articles and documents

One-pot synthesis of salicylanilides by direct amide bond formation from salicyclic acid under microwave irradiation

A highly efficient protocol for the preparation of aromatic amides is described by the direct reactions between salicyclic acid and aromatic amines in the presence of phosphorous trichloride under microwave irradiation. The method has several advantages over the conventional methods, including operational simplicity, good yield, and reduced reaction time.

Potential salicylamide antiplaque agents: In vitro antibacterial activity against Actinomyces viscosus

-

Studies on 2-hydroxythiobenzamide and 2-hydroxythiobenzanilide. 1. Synthesis of the compounds

-