262846-80-0Relevant academic research and scientific papers
Catalytic, enantioselective synthesis of α-aminonitriles with a novel zirconium catalyst
Ishitani, Haruro,Komiyama, Susumu,Kobayashi, Shu
, p. 3186 - 3188 (2007/10/03)
Strecker reactions of aldimines with Bu3SnCN in the presence of the novel chiral zirconium binuclear catalyst 1 provide α-aminonitriles in good yields and with high enantioselectivities. The reaction can be applied to a wide range of substrates. Since both enantiomers of the choral sources are readily available, both enantiomers of the α-aminonitriles are easily prepared according to this method. L = N-methylimidazole.
