299898-20-7Relevant academic research and scientific papers
Air-stable, storable, and highly selective chiral Lewis acid catalyst
Ueno, Masaharu,Ishitani, Haruro,Kobayashi, Shu
, p. 3395 - 3397 (2002)
(matrix presented) An air-stable storable, and highly selective chiral Lewis acid catalyst for asymmetric Mannich-type reactions has been developed. The catalyst can be stored for more than three months in air at room temperature without loss of activity.
The first allylation of imines with allyltrichlorosilanes using neutral coordinate-organocatalysts
Sugiura, Masaharu,Robvieux, Fabrice,Kobayashi, Shu
, p. 1749 - 1751 (2007/10/03)
Imines derived from aldehydes and 2-aminophenols reacted with allyltrichlorosilanes in the presence of DMF, HMPA, or pyridine N-oxide as a neutral coordinate-organocatalyst to afford the corresponding homoallylic amines in high yields with high stereosele
Catalytic enantioselective addition of propionate units to imines: An efficient synthesis of anti-α-methyl-β-amino acid derivatives
Kobayashi, Shu,Kobayashi, Jun,Ishiani, Haruro,Ueno, Masaharu
, p. 4185 - 4190 (2007/10/03)
Optically active anti-α-methyl-β-amino acid derivatives have been prepared based on catalytic enantioselective addition of propionate units to simple and inert imines using a chiral zirconium complex. High reactivity and selectivity with wide substrate sc
Catalytic, enantioselective synthesis of α-aminonitriles with a novel zirconium catalyst
Ishitani, Haruro,Komiyama, Susumu,Kobayashi, Shu
, p. 3186 - 3188 (2007/10/03)
Strecker reactions of aldimines with Bu3SnCN in the presence of the novel chiral zirconium binuclear catalyst 1 provide α-aminonitriles in good yields and with high enantioselectivities. The reaction can be applied to a wide range of substrates. Since both enantiomers of the choral sources are readily available, both enantiomers of the α-aminonitriles are easily prepared according to this method. L = N-methylimidazole.
