26293-27-6

Upstream product

• 26293-27-6 Trifluoro-acetic acid (S)-1-[(S)-1,2-bis-(2,2,2-trifluoro-acetoxy)-ethyl]-2,3-bis-(2,2,2-trifluoro-acetoxy)-propyl ester 
• 87-99-0 XYLITOL 
• 685-27-8 2,2,2-trifluoro-N-methyl-N-(2,2,2-trifluoroacetyl)acetamide 
• 407-25-0 trifluoroacetic anhydride 
• 488-81-3 Adonitol 
• 488-82-4 D-Arabitol 

Downstream Products

• 26293-27-6 trifluoroacetylated arabinitol 
• 26293-27-6 Trifluoro-acetic acid (S)-1-[(S)-1,2-bis-(2,2,2-trifluoro-acetoxy)-ethyl]-2,3-bis-(2,2,2-trifluoro-acetoxy)-propyl ester 

Relevant academic research and scientific papers

Capillary gas-chromatographic analysis of monosaccharides: Improvements and comparisons using trifluoroacetylation and trimethylsilylation of sugar O-benzyl- and O-methyl-oximes

Two new procedures for the gas-chromatographic analysis of monosaccharides are reported. One involves derivatization of the sugars by reaction with O-benzylhydroxylamine followed by trifluoroacetylation with N-methylbis(trifluoroacetamide) and chromatography on a DB-1701 capillary column. This technique probably provides the best resolution achieved to date of the C3-C6 aldoses, as well as of the corresponding alditols. Ketoses can be qualitatively analyzed by this method, but complications interfere with their quantitative analysis. The second procedure also involves initial derivatization as the O-benzyloxime, but is followed by trimethylsilylation with 1-trimethylsilylimidazole, and chromatography on a DB-17 column. This technique is particularly useful for C5 sugars, C6 ketoses, and mixtures of sugars, alditols, and/or lactones. A number of additional, critical, observations on the derivatization and capillary gas-chromatographic analysis of monosaccharides are described.

IMPROVED GAS CHROMATOGRAPHIC SEPARATION OF ENANTIOMERIC CARBOHYDRATE DERIVATIVES USING A NEW CHIRAL STATIONARY PHASE

Pentylated cyclomaltohexaose ( α-cyclodextrin ) can be used as a chiral stationary phase for cappilary g.l.c. in the range 40 deg to > 200 deg.Strong enantioselective molecular interactions are observed towards trifluoroacetylated carbohydrates, methyl glycosides, 1,4- and 1,5-anhydroalditols, polyols, and polyhydroxy acid methyl esters.Base-line resolution of enantiomers is achieved after only a few minutes.