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2-(4-Fluorophenoxy)-1-ethanamine(HCl) is a chemical compound characterized by a central ethanamine molecule with a fluorophenoxy group attached to it. The presence of HCl in its name signifies that it is a hydrochloride salt. 2-(4-Fluorophenoxy)-1-ethanamine(HCl) may serve as a building block for the synthesis of other organic compounds and has potential applications in the pharmaceutical and chemical industries, as well as in research and development for new drug formulations.

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  • 263409-81-0 Structure
  • Basic information

    1. Product Name: 2-(4-Fluorophenoxy)-1-ethanamine(HCl)
    2. Synonyms: 2-(4-Fluorophenoxy)-1-ethanamine(HCl)
    3. CAS NO:263409-81-0
    4. Molecular Formula: C8H11ClFNO
    5. Molecular Weight: 191.63
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 263409-81-0.mol
  • Chemical Properties

    1. Melting Point: 213-216℃
    2. Boiling Point: 282.8oC at 760 mmHg
    3. Flash Point: 124.8oC
    4. Appearance: /
    5. Density: N/A
    6. Vapor Pressure: 0.00251mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: Inert atmosphere,Room Temperature
    9. Solubility: N/A
    10. Sensitive: Hygroscopic
    11. CAS DataBase Reference: 2-(4-Fluorophenoxy)-1-ethanamine(HCl)(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2-(4-Fluorophenoxy)-1-ethanamine(HCl)(263409-81-0)
    13. EPA Substance Registry System: 2-(4-Fluorophenoxy)-1-ethanamine(HCl)(263409-81-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 263409-81-0(Hazardous Substances Data)

263409-81-0 Usage

Uses

Used in Pharmaceutical Industry:
2-(4-Fluorophenoxy)-1-ethanamine(HCl) is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure, featuring a fluorophenoxy group, can contribute to the development of new drugs with specific therapeutic properties.
Used in Chemical Industry:
In the chemical industry, 2-(4-Fluorophenoxy)-1-ethanamine(HCl) is utilized as a precursor in the production of specialty chemicals. Its versatility in chemical reactions allows for the creation of a range of products with diverse applications.
Used in Research and Development:
2-(4-Fluorophenoxy)-1-ethanamine(HCl) is employed as a research compound in the exploration of new drug candidates and chemical entities. Its potential role in medicinal chemistry makes it a valuable tool for scientists working on the discovery and optimization of novel therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 263409-81-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,3,4,0 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 263409-81:
(8*2)+(7*6)+(6*3)+(5*4)+(4*0)+(3*9)+(2*8)+(1*1)=140
140 % 10 = 0
So 263409-81-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H10FNO.ClH/c9-7-1-3-8(4-2-7)11-6-5-10;/h1-4H,5-6,10H2;1H

263409-81-0 Well-known Company Product Price

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  • Alfa Aesar

  • (H31410)  2-(4-Fluorophenoxy)ethylamine hydrochloride, 97%   

  • 263409-81-0

  • 250mg

  • 525.0CNY

  • Detail
  • Alfa Aesar

  • (H31410)  2-(4-Fluorophenoxy)ethylamine hydrochloride, 97%   

  • 263409-81-0

  • 1g

  • 1883.0CNY

  • Detail

263409-81-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-fluorophenoxy)ethanamine,hydrochloride

1.2 Other means of identification

Product number -
Other names 2-(4-fluorophenoxy)ethanamine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:263409-81-0 SDS

263409-81-0Downstream Products

263409-81-0Relevant articles and documents

HEPATITIS B CORE PROTEIN ALLOSTERIC MODULATORS

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Paragraph 000221, (2015/10/05)

ABSTRACT The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.

THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS

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Page/Page column 34, (2010/04/03)

The present invention provides thiazole derivatives as Stearoyl CoA Desaturase (SCD) inhibitors. In particular, the compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by Stearoyl CoA Desaturase

Development of a scalable synthesis of a nonbasic inhibitor of the serine protease tryptase

Dener, Jeffrey M.,O'Bryan, Colin,Yee, Robert,Shelton, Emma J.,Sperandio, David,Mahajan, Tania,Palmer, James T.,Spencer, Jeffrey R.,Tong, Zhiwei

, p. 4591 - 4595 (2007/10/03)

A chromatography-free process for the synthesis of a bis(benzimidazole)difluoromethane inhibitor of the serine protease tryptase is described. This synthesis features the introduction of the gem-difluoro moiety using the electrophilic fluorinating reagent N-fluoro-bis(phenylsulfonimide) as well as the stepwise introduction of both benzimidazole rings. A protocol for the destruction of reactive, process-related substances produced in the synthesis is also presented.

ETHER DERIVATIVE

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Page/Page column 29, (2008/06/13)

The present invention relates to an ether derivative represented by the formula (I), a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof wherein each symbol is as defined in the description, and an ether derivative represented by the formula (III), a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof wherein each symbol is as defined in the description; a pharmaceutical composition containing the ether derivative; and a package containing the pharmaceutical composition and a description of use thereof. A pharmaceutical composition of the present invention, which contains this compound of the present invention has a superior anti-inflammatory and analgesic activity and is useful as various pharmaceutical agents such as an anti-inflammatory agent, an analgesic, a therapeutic agent for inflammatory bowel disease, a therapeutic agent for pollakiuria and/or incontinentia, a therapeutic agent for asthma and the like.

HYDROXY-TETRAHYDRO-NAPHTHALENYLUREA DERIVATIVES

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Page 43-45, (2008/06/13)

This invention relates to hydroxy-tetrahydro-naphthalenylurea derivatives and salts thereof which are useful as active ingredients of pharmaceutical preparations. The hydroxy-tetrahydro-naphthalenylurea derivatives of the present invention have an excelle

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