26409-24-5Relevant academic research and scientific papers
ANTHOCYANIN SYNTHESIS PROMOTER AND CHLOROPHYLL DEGRADATION PROMOTER
-
Paragraph 0080; 0083, (2017/06/24)
PROBLEM TO BE SOLVED: To provide an anthocyanin synthesis promoter and a chlorophyll degradation promoter that are safe and practicable. SOLUTION: The present invention provides an anthocyanin synthesis promoter and a chlorophyll degradation promoter comprising extract of plant belonging to Hydrocharitaceae Egeria or Elodea. The extract preferably comprises at least one of a compound of formula (I) and a compound of formula (II) as an active compound. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT
Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach
Wu, Yu-Shan,Coumar, Mohane Selvaraj,Chang, Jang-Yang,Sun, Hsu-Yi,Kuo, Fu-Ming,Kuo, Ching-Chuan,Chen, Ying-Jun,Chang, Chi-Yen,Hsiao, Chia-Ling,Liou, Jing-Ping,Chen, Ching-Ping,Yao, Hsien-Tsung,Chiang, Yi-Kun,Tan, Uan-Kang,Chen, Chiung-Tong,Chu, Chang-Ying,Wu, Su-Ying,Yeh, Teng-Kuang,Lin, Chin-Yu,Hsieh, Hsing-Pang
supporting information; experimental part, p. 4941 - 4945 (2010/03/02)
BPR0L075 (2) is a potential anticancer drug candidate designed from Combretastatin A-4 (1) based on the bioisosterismprinciple.Metabolites of 2, proposed from in vitrohumanmicrosome studies,were synthesized, leading to the identification of metabolite-der
Multi-functionalization of gallic acid towards improved synthesis of α- and β-DDB
Alam, Ashraful,Takaguchi, Yutaka,Ito, Hideyuki,Yoshida, Takashi,Tsuboi, Sadao
, p. 1909 - 1918 (2007/10/03)
The synthesis of mono-, di- and trisubstituted gallic acids and their ester with similar or different groups including different acetal and ketals is described. Regioselective bromination on two ortho-positions of methyl gallate, which is very crucial for many organic syntheses, was achieved in high yield and purity. The α- and β-DDB were synthesized in high overall yield and purity from the regioselective bromoderivatives.
Total Syntheses of the Metabolites of Schizandrin
Tanaka, Masahide,Ikeya, Yukinobu,Mitsuhashi, Hiroshi,Maruno, Masao,Wakamatsu, Takeshi
, p. 11703 - 11724 (2007/10/02)
The total syntheses of the metabolites of schizandrin were achieved.The tetracyclic lactone intermediates (13a-e) were prepared in optically pure form by the oxidative coupling reaction of the corresponding 3-benzyl-2-benzylidenebutyrolactones.Mukaiyama hydration of 13b afforded hydroxylactone (14), which was converted into SZ-M3 (4).The introduction of C6,7-diol moiety, which is common to the metabolites (4-11), was carried out by the successive double bond migration to 15a-e, lactone ring reduction ot the allylic diols (32a-e), and glycol formation.Then, reduction of the mesylates 33 completed the syntheses of the metabolites.
Intramolecular Oxidative Coupling of Aromatic Compounds. I Oxidation of Diphenolic Substrates
Krauss, Adrian S.,Taylor, Walter C.
, p. 1307 - 1333 (2007/10/02)
The synthesis of (2RS,3SR)-1-(3,5-dihydroxy-4-methoxyphenyl)-(4-hydroxy-3,5-dimethoxyphenyl)2,3-dimethylbutan-1-one (26) is described.Diphenolic oxidative coupling of (26) did not produce a eupodienone-type product.An aryltetralin derivative was formed in
Biosynthesis. Part 24. Speculative Incorporation Experiments with 1-Benzylisoquinolines and a Logical Approach via C6-C2 and C6-C3 Precursors to the Biosynthesis of Hasubanonine and Protostephanine
Battersby, Alan R.,Jones, Raymond C. F.,Kazlauskas, Rymantas,Thornber, Craig W.,Ruchirawat, Somsak,Staunton, James
, p. 2016 - 2029 (2007/10/02)
Many possible 1-benzyltetrahydroisoquinolines have been examined as possible advanced precursors of the alkaloids hasubanonine (1) and protostephanine (2) in Stephania japonica plants, but none was incorporated significantly.Administration of various precursor molecules having only one aromatic ring, such as tyrosine, has demonstrated that both alkaloids are derived from two different C6-C2 biogenetic units.The subsequent failure of further 1-benzyltetrahydroisoquinolines and bisphenethylamines to be incorporated suggested the intermediacy of either (a) modified 1-benzylisoquinolines or (b) trioxygenated C6-C2 building blocks.Precursors designed to examine the first possibility, such as 1-benzyl-3,4-dihydroisoquinolines or 1-benzyl-1-carboxytetrahydroisoquinolines, were not incorporated into (1) and (2) whereas two 3',4',5'-trioxygenated 2-phenylethylamines were incorporated.These findings allow further delineation of the requirements for later precursors of the alkaloids (1) and (2).
