57230-04-3

Usage

Uses

Used in Pharmaceutical Industry:
3-(Benzyloxy)-4,5-dimethoxybenzaldehyde is used as an intermediate in the synthesis of metabolites of Trimethoprim (T795615), an antibacterial agent. It is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections. 3-(BENZYLOXY)-4,5-DIMETHOXYBENZALDEHYDE's unique structure allows for the development of effective treatments against bacterial infections, contributing to the overall improvement of public health.

Upstream product

• 29865-90-5 3-hydroxy-4,5-dimethoxybenzaldehyde 
• 100-39-0 benzyl bromide 
• 3934-87-0 5-hydroxyvanillin 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 121-33-5 vanillin 
• 7632-62-4 3-benzyloxy-4,5-dimethoxybenzyl alcohol 
• 77-78-1 dimethyl sulfate 
• 51425-83-3 N’-(3-(benzyloxy)-4,5-dimethoxybenzoyl)benzenesulfonohydrazide 
• 99-24-1 methyl galloate 
• 79831-86-0 methyl 3-(benzyloxy)-4,5-dihydroxybenzoate 
• 26409-24-5 methyl 3-benzyloxy-4,5-dimethoxybenzoate 
• 101289-41-2 3-benzyloxy-4,5-dihydroxybenzoic acid hydrazide 
• 100-44-7 benzyl chloride 

Downstream Products

• 5164-97-6 1-benzyloxy-2,3-dimethoxy-5-[(E)-2-nitrovinyl]benzene 
• 212116-74-0 (Z)-2,3'-dibenzyloxy-4',5'-dimethoxystilbene 
• 212116-75-1 (E)-2,3'-dibenzyloxy-4',5'-dimethoxystilbene 
• 7632-62-4 3-benzyloxy-4,5-dimethoxybenzyl alcohol 
• 912957-28-9 Viscolin 
• 1357024-86-2 (E)-3-(4-(benzyloxy)-2,3,6-trimethoxyphenyl)-1-(4-(benzyloxy)-3-methoxyphenyl)-prop-2-en-1-one 
• 1357024-85-1 2-(benzyloxy)-3,4,6-trimethoxybenzaldehyde 
• 52249-82-8 4-(benzyloxy)-2,3,6-trimethoxybenzaldehyde 
• 855242-15-8 1-(benzyloxy)-2,3,5-trimethoxybenzene 
• 1426838-52-9 1-(4-bromophenyl)-7-(3-hydroxy-4,5-dimethoxyphenyl)heptane-3,5-dione 
• 1426838-81-4 C₂₈H₂₉BrO₅ 
• 1426838-80-3 7-(3-(benzyloxy)-4,5-dimethoxyphenyl)-1-(4-bromophenyl)-5-hydroxyheptan-3-one 
• 1426838-79-0 3-(3-(benzyloxy)-4,5-dimethoxyphenyl)propanal 
• 1426838-78-9 ethyl 3-(3-(benzyloxy)-4,5-dimethoxyphenyl)propanoate 

Relevant academic research and scientific papers

Isoquinoline Derivatives, Methods of Synthesis and Uses Thereof

Described herein are compounds, pharmaceutical compositions and methods of using these compounds and pharmaceutical compositions for treating and/or preventing conditions such as amyotrophic lateral sclerosis. These compounds and pharmaceutical compositions are also useful as antivirals and antimicrobial agents.

ANTHOCYANIN SYNTHESIS PROMOTER AND CHLOROPHYLL DEGRADATION PROMOTER

PROBLEM TO BE SOLVED: To provide an anthocyanin synthesis promoter and a chlorophyll degradation promoter that are safe and practicable. SOLUTION: The present invention provides an anthocyanin synthesis promoter and a chlorophyll degradation promoter comprising extract of plant belonging to Hydrocharitaceae Egeria or Elodea. The extract preferably comprises at least one of a compound of formula (I) and a compound of formula (II) as an active compound. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT

A concise synthesis of viscolin, and its anti-inflammatory effects through the suppression of iNOS, COX-2, ERK phosphorylation and proinflammatory cytokines expressions

In the present report, a concise synthesis of viscolin (1) has been achieved. The anti-inflammatory effect of viscolin was investigated in vitro and in vivo. Viscolin blocked the expression of iNOS and COX-2, and it also inhibited the ERK for the activation of NF-κB in LPS-stimulated RAW 264.7 macrophages. Western blotting and immunohistochemical analysis revealed that viscolin decreased Carr-induced iNOS and COX-2 expressions. These results could help to deduce the anti-inflammatory mechanisms.

Biosynthesis of yatein in Anthriscus sylvestris.

Little is known about the biosynthesis of yatein, in spite of its importance as a typical heartwood lignan and a key biosynthetic intermediate of the antitumor lignan podophyllotoxin. The present study, based on individual administration of [13C]phenylalanine and deuterium labelled lignans and simultaneous administration of two distinct lignans labelled with deuterium atoms to Anthriscus sylvestris, established the two independent branch pathways from matairesinol, one to afford yatein via thujaplicatin, 5-methylthujaplicatin, and 4,5-dimethylthujaplicatin and the other to bursehernin via pluviatolide. The latter pathway did not lead to yatein, eliminating the presence of a metabolic grid from matairesinol to yatein.

Compositions containing aromatic aldehydes and their use in treatments

Disclosed are pharmaceutical and cosmetic compositions containing aromatic aldehyde compounds. Some of the disclosed compositions are useful as topical therapeutics for treating inflammatory dermatologic conditions. Some of the compositions are useful in transdermal and other systemic dose forms for treating other inflammatory conditions in mammals.

A bibenzyl from Empetrum nigrum

A new bibenzyl, 1-(2-hydroxyphenyl)-2-(3-hydroxy-4,5-dimethoxyphenyl)- ethane, possessing similar germination inhibitory activity to batatasin III in vitro, was isolated from the leaves of Empetrum nigrum. The isolation, structural determination and synth

New Agents of Biaryl Oxidative Coupling in Fluoro Acid Medium. VI. Application to the Synthesis of Phenolic Bisbenzocyclooctadiene Lignans

A systematic study of redox couples in fluoro acid medium has been carried out for the oxidative coupling of bisbenzocyclooctadiene lignan precursors.Tl2O3 and Re2O7 were found to be the more efficient reagents with precursors possessing methylenedioxy substituents for the former and only methoxy groups for the latter.Finally, oxidative coupling of a phenolic dibenzylbutane led to a mixture of two BBCOD's, resulting from para and ortho coupling to the phenolic group. - Keywords: Bisbenzocyclooctadienes, Biaryls, Dibenzylbutanolides, Dibenzylbutanes, Phenolic coupling.

Intramolecular Oxidative Coupling of Aromatic Compounds. I Oxidation of Diphenolic Substrates

The synthesis of (2RS,3SR)-1-(3,5-dihydroxy-4-methoxyphenyl)-(4-hydroxy-3,5-dimethoxyphenyl)2,3-dimethylbutan-1-one (26) is described.Diphenolic oxidative coupling of (26) did not produce a eupodienone-type product.An aryltetralin derivative was formed in

Biosynthesis. Part 24. Speculative Incorporation Experiments with 1-Benzylisoquinolines and a Logical Approach via C6-C2 and C6-C3 Precursors to the Biosynthesis of Hasubanonine and Protostephanine

Many possible 1-benzyltetrahydroisoquinolines have been examined as possible advanced precursors of the alkaloids hasubanonine (1) and protostephanine (2) in Stephania japonica plants, but none was incorporated significantly.Administration of various precursor molecules having only one aromatic ring, such as tyrosine, has demonstrated that both alkaloids are derived from two different C6-C2 biogenetic units.The subsequent failure of further 1-benzyltetrahydroisoquinolines and bisphenethylamines to be incorporated suggested the intermediacy of either (a) modified 1-benzylisoquinolines or (b) trioxygenated C6-C2 building blocks.Precursors designed to examine the first possibility, such as 1-benzyl-3,4-dihydroisoquinolines or 1-benzyl-1-carboxytetrahydroisoquinolines, were not incorporated into (1) and (2) whereas two 3',4',5'-trioxygenated 2-phenylethylamines were incorporated.These findings allow further delineation of the requirements for later precursors of the alkaloids (1) and (2).