264132-30-1

Basic information

• Product Name: (2S,3S,6R)-6-[(1S)-1-benzyloxymethoxyethyl]-3-phenyl-3,6-dihydro-2H-pyran-2-carboxylic acid 2,2,2-trichloroethyl ester
• Synonyms: (2S,3S,6R)-6-[(1S)-1-benzyloxymethoxyethyl]-3-phenyl-3,6-dihydro-2H-pyran-2-carboxylic acid 2,2,2-trichloroethyl ester
• CAS NO: 264132-30-1
• Molecular Weight: 499.819
• Mol File: 264132-30-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S,6R)-6-[(1S)-1-benzyloxymethoxyethyl]-3-phenyl-3,6-dihydro-2H-pyran-2-carboxylic acid 2,2,2-trichloroethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,6R)-6-[(1S)-1-benzyloxymethoxyethyl]-3-phenyl-3,6-dihydro-2H-pyran-2-carboxylic acid 2,2,2-trichloroethyl ester(264132-30-1)
• EPA Substance Registry System: (2S,3S,6R)-6-[(1S)-1-benzyloxymethoxyethyl]-3-phenyl-3,6-dihydro-2H-pyran-2-carboxylic acid 2,2,2-trichloroethyl ester(264132-30-1)

Safety Data

• Hazardous Substances Data: 264132-30-1(Hazardous Substances Data)

Upstream product

• 264132-24-3 (1S,2S,3E)-1-[(1S)-1-benzyloxymethoxyethyl]-2-hydroxy-4-phenylbut-3-enyloxyacetic acid tert-butyl ester 
• 264132-27-6 (5S,6S)-5-((S)-1-Benzyloxymethoxy-ethyl)-6-((E)-styryl)-[1,4]dioxan-2-one 
• 15799-66-3 trans-β-triphenylstannylstyrene 
• 115-20-8 1,1,1-trichloroethanol 
• 264132-28-7 (2S,3S,6R)-6-[(1S)-1-benzyloxymethoxyethyl]-3-phenyl-3,6-dihydro-2H-pyran-2-carboxylic acid 

Downstream Products

• 264132-48-1 C₃₀H₃₁Cl₃O₇ 
• 264132-45-8 C₃₈H₃₉Cl₃O₈ 
• 264132-20-9 C₄₂H₄₂O₉ 
• 264132-57-2 C₄₂H₄₄O₁₀ 
• 264132-54-9 C₄₄H₄₅Cl₃O₁₀ 
• 264132-51-6 C₅₂H₅₃Cl₃O₁₁ 
• 264132-32-3 (2S,3S,6R)-6-[(1S)-1-hydroxyethyl]-3-phenyl-3,6-dihydro-2H-pyran-2-carboxylic acid 2,2,2-trichloroethyl ester 

Relevant articles and documents

Synthesis and Study of C3-Symmetric Hydropyran Cyclooligolides with Oriented Aryl and Alcohol Appendages at 10 A Spacing

Modular syntheses of C3-symmetric macrocycles with pendant aryl and hydroxymethyl groups are described. These functional groups, amenable to further elaboration, were installed early in each synthesis and carried through an iterative sequence of module coupling and macrolactonization. Association constants for macrolides 1a-c with alkali metal cation guests were determined, and sandwich-type complexes with Ba2+ were confirmed for these macrocycles based on 1H NMR studies, including Job plots. X-ray crystallographic data for macrolides 1a and 1c were obtained and are discussed in detail. These data provide support that the macrolides are structurally well-defined and preorganized for binding the potassium cation. Preparation of the tris(bromoacetylated) macrotriolide 43 exemplifies a functionalized platform suitable for elaboration with peptide or carbohydrate residues.