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264224-08-0

3-[(4-nitrophenyl)thio]benzoic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 264224-08-0 Structure

  • Basic information

    1. Product Name: 3-[(4-nitrophenyl)thio]benzoic acid
    2. Synonyms: 3-[(4-nitrophenyl)thio]benzoic acid
    3. CAS NO:264224-08-0
    4. Molecular Formula:
    5. Molecular Weight: 275.285
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 264224-08-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-[(4-nitrophenyl)thio]benzoic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-[(4-nitrophenyl)thio]benzoic acid(264224-08-0)
    11. EPA Substance Registry System: 3-[(4-nitrophenyl)thio]benzoic acid(264224-08-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 264224-08-0(Hazardous Substances Data)

264224-08-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 264224-08-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,4,2,2 and 4 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 264224-08:
(8*2)+(7*6)+(6*4)+(5*2)+(4*2)+(3*4)+(2*0)+(1*8)=120
120 % 10 = 0
So 264224-08-0 is a valid CAS Registry Number.

264224-08-0Relevant articles and documents

Novel dengue virus NS2B/NS3 protease inhibitors

Wu, Hongmei,Bock, Stefanie,Snitko, Mariya,Berger, Thilo,Weidner, Thomas,Holloway, Steven,Kanitz, Manuel,Diederich, Wibke E.,Steuber, Holger,Walter, Christof,Hofmann, Daniela,Wei?brich, Benedikt,Spannaus, Ralf,Acosta, Eliana G.,Bartenschlager, Ralf,Engels, Bernd,Schirmeister, Tanja,Bodem, Jochen

, p. 1100 - 1109 (2015)

Dengue fever is a severe, widespread, and neglected disease with more than 2 million diagnosed infections per year. The dengue virus NS2B/NS3 protease (PR) represents a prime target for rational drug design. At the moment, there are no clinical PR inhibitors (PIs) available. We have identified diaryl (thio)ethers as candidates for a novel class of PIs. Here, we report the selective and noncompetitive inhibition of the serotype 2 and 3 dengue virus PR in vitro and in cells by benzothiazole derivatives exhibiting 50% inhibitory concentrations (IC50s) in the low-micromolar range. Inhibition of replication of DENV serotypes 1 to 3 was specific, since all substances influenced neither hepatitis C virus (HCV) nor HIV-1 replication. Molecular docking suggests binding at a specific allosteric binding site. In addition to the in vitro assays, a cell-based PR assay was developed to test these substances in a replication-independent way. The new compounds inhibited the DENV PR with IC50s in the low-micromolar or submicromolar range in cells. Furthermore, these novel PIs inhibit viral replication at submicromolar concentrations.

Novel method and compounds

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Page/Page column 24, (2010/02/05)

A method for the treatment of conditions associated with a need for inhibition of GSK-3, such as diabetes, dementias such as Alzheimer's disease and manic depression which method comprises the administration of a pharmaceutically effective, non-toxic amou

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