264909-80-0

Upstream product

• 264909-77-5 N-(2-bromo-4-methoxyanilinomethyl)succinimide 
• 264909-78-6 2-bromo-4-methoxy-N-methylaniline 
• 2537-48-6 diethyl 1-cyanomethylphosphonate 
• 264909-79-7 2-bromo-4-methoxy-N-methylpyruvanilide 
• 32338-02-6 2-bromo-4-methoxyaniline 

Relevant academic research and scientific papers

A new efficient route to (±)-physostigmine and (±)-physovenine by means of 5-exo selective aryl radical cyclization of o-bromo-N- acryloylanilides

Bu3SnH-mediated aryl radical cyclization of o-bromo-N-acryloylanilides 16 and 17 proceeded in a 5-exo manner exclusively to give, in high yields, oxindoles 3 and 4, the key intermediates for the synthesis of (±)- physostigmine and (±)-physoveni