264909-79-7

Upstream product

• 264909-77-5 N-(2-bromo-4-methoxyanilinomethyl)succinimide 
• 32338-02-6 2-bromo-4-methoxyaniline 
• 264909-78-6 2-bromo-4-methoxy-N-methylaniline 
• 5704-66-5 pyruvoyl chloride 

Downstream Products

• 264909-81-1 methyl 3-(2'-bromo-4'-methoxyphenyl-N-methylcarbamoyl)-3-methyl-2-butenoate 
• 264909-80-0 2'-bromo-4'-methoxy-N-methyl-3-cyano-2-methylpropenanilide 

Relevant academic research and scientific papers

A new efficient route to (±)-physostigmine and (±)-physovenine by means of 5-exo selective aryl radical cyclization of o-bromo-N- acryloylanilides

Bu3SnH-mediated aryl radical cyclization of o-bromo-N-acryloylanilides 16 and 17 proceeded in a 5-exo manner exclusively to give, in high yields, oxindoles 3 and 4, the key intermediates for the synthesis of (±)- physostigmine and (±)-physoveni