264909-79-7Relevant academic research and scientific papers
A new efficient route to (±)-physostigmine and (±)-physovenine by means of 5-exo selective aryl radical cyclization of o-bromo-N- acryloylanilides
Ishibashi, Hiroyuki,Kobayashi, Tetsuya,MacHida, Noriko,Tamura, Osamu
, p. 1469 - 1473 (2007/10/03)
Bu3SnH-mediated aryl radical cyclization of o-bromo-N-acryloylanilides 16 and 17 proceeded in a 5-exo manner exclusively to give, in high yields, oxindoles 3 and 4, the key intermediates for the synthesis of (±)- physostigmine and (±)-physoveni
