265119-91-3

Upstream product

• 119866-78-3 methyl 3,3,3-trifluoro-2-(phenylamino)-propanoate 
• 110920-05-3 methyl ester of 2-(N-phenylimino)trifluoropropanoic acid 
• 622-37-7 Phenyl azide 
• 13858-07-6 4-iodo-3-phenyl-1,2,3-λ⁵-oxadiazol-3-ium-5-olate 
• 2325-27-1 N-phenyltriphenyliminophosphorane 
• 1396123-83-3 3-phenyl-4-(trifluoromethyl)-1,2,3-λ⁵-oxadiazol-3-ium-5-olate 
• 347389-74-6 2-ethynyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 
• 1396123-82-2 3,3,3-trifluoro-2-(phenylamino)propanoic acid 

Relevant academic research and scientific papers

Synthesis of 4-fluoromethylsydnones and their participation in alkyne cycloaddition reactions

We report the synthesis and some structural studies of 4-trifluoromethyl, 4-difluoromethyl-, and 4-monofluoromethylsydnones. All but the latter compounds are stable and represent effective precursors to a range of pyrazoles after cycloaddition reactions with alkynes. The cycloadditions are generally highly regioselective and provide 5-fluoromethylpyrazole products, although we have observed that Bn-substituted sydnones can provide an unexpected alkyne insertion mode that generates the 3-fluoromethyl isomer.

Alkoxypyrazoles and the process for their preparation

The present invention relates to a alkoxypyrazoles preparation process, and new alkoxypyrazole compounds.