26537-65-5Relevant articles and documents
Synthesis and evaluation of phenyl substituted sydnones as potential DPPH-radical scavengers
Mallur, Shanta G.,Tiwari,Raju, B. China,Babu, K. Suresh,Ali, A. Zehra,Sastry,Rao, J. Madhusudana
, p. 1686 - 1689 (2008/09/19)
A series of phenyl substituted sydnones has been synthesized and their radical-scavenging activity has been studied on DPPH free radical. Out of eighteen compounds screened, nine compounds show interesting activity. A mechanism is presented whereby sydnones scavenge DPPH radical through donating H-atom at 4th-position. Its strong radical-scavenging activity mainly arises from 1, 2, 3-oxadiazolium-5-olate ring. Different substituents and their positions on the phenyl ring differently influence DPPH scavenging activity and therefore, may provide clues to design and develop better free-radical scavenging sydnones with multiple activities.
The Efficient Synthesis of 3-Arylsydnones Under Neutral Conditions
Applegate, Jacqueline,Turnbull, Kenneth
, p. 1011 - 1012 (2007/10/02)
Various substituted aryl sydnones can be prepared in high yield under mild, neutral conditions by nitrosation of the appropriate aryl glycine with isoamyl nitrite in dimethoxyethane followed by cyclization with trifluoroacetic anhydride.
Debromination of 3-Aryl-4-bromosydnones with Sodium Borohydride
Turnbull, Kenneth
, p. 334 - 336 (2007/10/02)
Debromination of 4-bromo-3-(2-substituted aryl) sydnones 1 with sodium borohydride in methanol occurs readily to give good yields of the corresponding parent sydnones 2, except in those cases where the aryl substituent also reacts.The utility of the proce
