2654-66-2

Basic information

• Product Name: 1-benzyl-2-methylpyridinium bromide
• Synonyms: 1-benzyl-2-methylpyridinium bromide;1-Benzyl-2-picolinium bromide
• CAS NO: 2654-66-2
• Molecular Formula: Br*C₁₃H₁₄N
• Molecular Weight: 264.16096
• EINECS: 220-182-7
• Mol File: 2654-66-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-benzyl-2-methylpyridinium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-2-methylpyridinium bromide(2654-66-2)
• EPA Substance Registry System: 1-benzyl-2-methylpyridinium bromide(2654-66-2)

Safety Data

• Hazardous Substances Data: 2654-66-2(Hazardous Substances Data)

Usage

Explanation

Different sources of media describe the Explanation of 2654-66-2 differently. You can refer to the following data:
1. The compound consists of 14 carbon atoms, 16 hydrogen atoms, 1 bromine atom, and 1 nitrogen atom in a single molecule.
2. The International Union of Pure and Applied Chemistry (IUPAC) provides a standardized nomenclature for chemical compounds. In this case, the compound is named as a derivative of pyridine with a benzyl group at position 1 and a methyl group at position 2, combined with a bromide ion.
3. This compound contains a positively charged nitrogen atom, which is bonded to four other atoms or groups, making it a quaternary ammonium salt.
4. 1-benzyl-2-methylpyridinium bromide is commonly used in organic synthesis reactions to facilitate the transfer of a reactant or product between immiscible phases (e.g., between aqueous and organic phases), thus increasing the reaction efficiency.
5. Due to its quaternary ammonium salt structure, 1-benzyl-2-methylpyridinium bromide can reduce surface tension between liquids, making it useful as a surfactant in various applications.
6. The compound has antibacterial properties, which make it suitable for use as a disinfectant and an antibacterial agent in various applications, including dental materials.
7. Researchers have explored the use of 1-benzyl-2-methylpyridinium bromide in the field of nanotechnology, although specific applications are not mentioned in the provided material.
8. Due to its unique chemical properties, 1-benzyl-2-methylpyridinium bromide has a wide range of industrial and research applications, including its use as a catalyst, surfactant, disinfectant, and potential applications in nanotechnology and dental materials.

Type of compound

Quaternary ammonium salt

InChI:InChI=1/C13H14N.BrH/c1-12-7-5-6-10-14(12)11-13-8-3-2-4-9-13;/h2-10H,11H2,1H3;1H/q+1;/p-1

Upstream product

• 109-04-6 2-bromo-pyridine 
• 109-06-8 α-picoline 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 149070-87-1 (S)-N-benzyl-2-methylpiperidine 
• 1443117-96-1 C₁₃H₁₆⁽²⁾H₃N 
• 777-38-8 1-benzyl-2-methylpiperidine 
• 89873-77-8 1-Benzyl-cis-2-propyl-6-methyl-4-piperideine 
• 89873-76-7 1-Benzyl-trans-2-propyl-6-methyl-4-piperideine 
• 89873-75-6 1-Benzyl-cis-2-propyl-6-methyl-3-piperideine 
• 89873-74-5 (+/-)-trans-1-benzyl-2-methyl-6-propyl-1,2,3,6-tetrahydropyridine 
• 89873-66-5 cis-1-Benzyl-2-cyano-6-methylpiperidine 
• 89873-65-4 trans-1-benzyl-6-methylpiperidine-2-carbonitrile 
• 84268-83-7 1-Benzyl-2-cyano-6-methyl-3-piperideine 
• 89873-73-4 1-Benzyl-6-methyl-2-propyl-1,2,5,6-tetrahydro-pyridine-2-carbonitrile 
• 89873-68-7 trans-1-Benzyl-2-cyano-4-piperideine 
• 89873-52-9 1-Benzyl-6-methyl-1,2,5,6-tetrahydropyridine N-oxide 
• 89873-78-9 1-Benzyl-6-methyl-1,2,5,6-tetrahydropyridine 

Relevant articles and documents

Synthesis of Enantioenriched 2-Alkyl Piperidine Derivatives through Asymmetric Reduction of Pyridinium Salts

An Ir-catalyzed enantioselective hydrogenation of 2-alkyl-pyridines has been developed using ligand MeO-BoQPhos. High levels of enantioselectivities up to 93:7 er were obtained. The resulting enantioenriched piperidines can be readily converted into biologically interesting molecules such as the fused tricyclic structures 5, 6, and 7 in 99:1 er, providing a novel, concise synthetic route to this family of chiral piperidine-containing compounds.

Efficient and chemoselective reduction of pyridines to tetrahydropyridines and piperidines via rhodium-catalyzed transfer hydrogenation

Promoted by iodide anion the rhodium complex dimer, [Cp RhCl 2]2, catalyzes efficiently the transfer hydrogenation of various quaternary pyridinium salts under mild conditions, affording not only piperidines but also 1,2,3,6-tetrahydropyridines in a highly chemoselective fashion, depending on the substitution pattern at the pyridinium ring. The reduction is conducted in azeotropic formic acid/triethylamine (HCOOH-Et 3N) mixture at 40 °C, with catalyst loadings as low as 0.005mol% being feasible. Copyright

COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF

Provided herein are compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, psychiatric disorders, neuromuscular disorders, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds provided herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.