26549-65-5

Usage

Uses

Used in Organic Synthesis:
N,N,N',N'-Tetramethyl-L-tartramide is used as a synthetic building block for the creation of various organic compounds. Its application in this field is due to its unique chemical structure, which allows for the formation of new molecules with specific properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N,N',N'-Tetramethyl-L-tartramide is used as an intermediate in the synthesis of certain drugs. Its role in this industry is to facilitate the production of medications by providing a key component in their chemical makeup.
Used in Chemical Research:
N,N,N',N'-Tetramethyl-L-tartramide is also utilized in chemical research as a model compound for studying various reaction mechanisms and understanding the behavior of similar molecules. This application is valuable for advancing the knowledge of chemical reactions and the development of new synthetic methods.

Upstream product

• 608-69-5 dimethyl meso-tartrate 
• 124-40-3 dimethyl amine 
• 21066-72-8 diethyl tartrate 
• 622-00-4 dibenzyl (2R,3R)-2,3-dihydroxybutanedioate 
• 87-91-2 diethyl (2R,3R)-tartrate 
• 87-69-4 L-Tartaric acid 

Downstream Products

• 63126-35-2 (R,R)-(+)-2,3-Dibenzyloxy-N,N,N',N'-tetramethylbernsteinsaeure-diamid 
• 26549-29-1 (R,R)-(+)-2,3-Dimethoxy-N,N,N',N'-tetramethylbernsteinsaeure-diamid 
• 141376-10-5 (4R,5R)-2-Methyl-2-phenyl-[1,3]dioxolane-4,5-dicarboxylic acid bis-dimethylamide 
• 141376-11-6 (4R,5R)-2-Phenyl-[1,3]dioxolane-4,5-dicarboxylic acid bis-dimethylamide 
• 141376-07-0 (4R,5R)-2-o-Tolyl-[1,3]dioxolane-4,5-dicarboxylic acid bis-dimethylamide 
• 88454-84-6 (2R,3R)-N,N,N',N'-Tetramethyl-2,3-bis<2-<2-(benzyloxy)ethoxy>ethyl>tataramide 
• 88454-99-3 (2R,3R,11R,12R)-N,N,N',N'-Tetramethyl-11,12-bis<(benzyloxy)methyl>-1,4,7,10,13,16-hexaoxacyclooctadecane-2,3-dicarboxamide 
• 141376-06-9 (4R,5R)-2-Methyl-2-o-tolyl-[1,3]dioxolane-4,5-dicarboxylic acid bis-dimethylamide 
• 63126-29-4 (4R,5R)-2,2,N,N,N',N'-hexamethyl-1,3-dioxolane-4,5-dicarboxamide 
• 1417715-01-5 O,O'-di(α-dibenzylamino-α-phenylacetyl)-N,N,N',N'-tetramethyl-L-tartaric diamide 
• 1417715-05-9 O,O'-di(α-bromo-α-phenylacetyl)-N,N,N',N'-tetramethyl-L-tartaric diamide 
• 1192797-44-6 N,N,N',N'-tetramethyl (R,R)-tartramide monotrityl ether 
• 26549-22-4 (-)-2,3-dimethoxy-1,4-bis(dimethylamino)butane 
• 26549-21-3 (S,S)-(+)-N,N,N',N'-tetramethyl-1,4-diamino-2,3-dimethoxybutane 

Relevant academic research and scientific papers

From single molecule to crystal: Mapping out the conformations of tartaric acids and their derivatives

Stereoisomers of one of the most important organic compounds, tartaric acid, optically active and meso as well as the ester or amide derivatives, can show diverse structures related to the rotation around the three carbon-carbon bonds. This study determin

Factors affecting conformation of (R,R)-tartaric acid ester, amide and nitrile derivatives. X-Ray diffraction, circular dichroism, nuclear magnetic resonance and ab initio studies

Derivatives 2a-15a of(R,R)-tartaric acid (la) with all combinations of methyl ester. amide. N-methylamide and N,N-dimethylamide groups, as well as the corresponding O,O-dibenzoyl derivatives 1b-15b and nitriles 16-18 have been synthesized. Their conformations have been studied by the NMR and CD methods in solution as well as by X-ray diffraction in the crystalline state. The preference for planar. T conformation of the four carbon chain is observed under conditions restricting the α-hydroxyacid, ester or amide group to be nearly planar. This conformation being stabilized by intramolecular hydrogen bonds of the S(5) motif and the electrostatic CO/C(β)H and CN/C(β)H coplanar bond interactions. The C=O/C(α)-O bond system tends to be either synplanar tester, acid), or antiplanar tester, primary and secondary amide). Ab initio calculations allowed to demonstrate that for the isolated molecules of diamides 10a and 15a there is strong preference for gauche C+(a,a) conformers, the driving force being the formation of the hydrogen bonded six-membered cycles of tire S(G) motif joining the OH and C=O groups from two different halves of the molecule. The results compare favourably with the experimental values derived from NMR spectra of 15a in nonpolar solvent. In the absence of intramolecular hydrogen bonding the N,N-dimethylamide group is better accommodated in a gauche G- conformer. This releases the nonbonded interaction due to the amide methyl group anti to the carbonyl group.

PENTACO-ORDINATE ORGANOSILICON COMPOUNDS IN SYNTHESIS: ASYMMETRIC REDUCTION OF CARBONYL COMPOUNDS WITH HYDROSILANES CATALYZED BY CHIRAL BASES

Reduction of carbonyl compounds with trialkoxysilane can be readily catalyzed by alkoxides of alkali metal.A considerable high asymmetric induction takes place by use of optically active diolates or even N-lithio 2-amino alcoholates derived from optically