265986-57-0Relevant academic research and scientific papers
Preparation of 5-Fluoropyrazoles from Pyrazoles and N -Fluorobenzenesulfonimide (NFSI)
Levchenko, Vitalina,Dmytriv, Yurii V.,Tymtsunik, Andriy V.,Liubchak, Konstantin,Rudnichenko, Alexander,Melnyk, Anton V.,Veselovych, Stanislav Y.,Borodulin, Yurii V.,Otsalyuk, Oleksandr M.,Tolmachev, Andrei A.,Mykhailiuk, Pavel K.
, p. 3265 - 3274 (2018/03/25)
Facile synthesis of 5-fluoropyrazoles by direct fluorination of pyrazoles with N-fluorobenzenesulfonimide (NFSI) was elaborated. This approach was used to prepare the unsubstituted 5-fluoro-1H-pyrazole, the known fungicide Penflufen, and many functionaliz
Fluorine-sacrificial cyclizations as an access to 5-fluoropyrazoles
Volle, Jean-Noel,Schlosser, Manfred
, p. 823 - 828 (2007/10/03)
Methyl 3-methoxy-2-trifluoromethylacrylate 1, readily prepared by Wittig reaction from methyl 3,3,3-trifluoropyruvate, has been treated with a number of aryl- (or hetaryl-) hydrazines. Under mild base-catalysis, the resulting 3-hydrazinoacrylates 6 underg
