26646-51-5

Usage

Uses

Used in Pharmaceutical Industry:
3-(3-METHYLPHENOXY)PROPAN-1-AMINE HYDROCHLORIDE is used as a chemical intermediate for the synthesis of other organic compounds, playing a crucial role in the development of new pharmaceuticals. Its specific applications in medicine are still under investigation, but its unique structure suggests it may contribute to the creation of novel therapeutic agents.
As the provided materials do not specify different applications in various industries or detailed uses beyond its role as a pharmaceutical intermediate, the description and uses are consolidated under the pharmaceutical industry. Further research and development may reveal additional applications and industries where 3-(3-METHYLPHENOXY)PROPAN-1-AMINE HYDROCHLORIDE could be beneficial.

InChI:InChI=1/C10H15NO/c1-9-4-2-5-10(8-9)12-7-3-6-11/h2,4-5,8H,3,6-7,11H2,1H3/p+1

Upstream product

• 6276-54-6 3-chloropropylamine hydrochloride 
• 108-39-4 3-methyl-phenol 

Downstream Products

• 119023-23-3 2-(3-m-Tolyloxy-propylamino)-3H-quinazolin-4-one 
• 103524-59-0 alpha-isopropyl-alpha-[3-[N-[3-(3-methylphenoxy)propyl]-N-methylamino]propyl]-3,4,5-trimethoxyphenylacetonitrile 
• 93793-83-0 Gastralgin 
• 103524-58-9 2-Isopropyl-5-(3-m-tolyloxy-propylamino)-2-(3,4,5-trimethoxy-phenyl)-pentanenitrile 

Relevant academic research and scientific papers

Preparation method of roxatidine acetate hydrochloride

The invention relates to a preparation method of roxatidine acetate hydrochloride. The preparation method comprises the following steps: step 1, dissolving m-cresol and 3-chloropropylamine hydrochloride into a reaction solvent according to a certain ratio, carrying out a reaction in the presence of an alkali, extracting after the reaction, and concentrating after simple purification to obtain an intermediate 1; 2, dissolving the intermediate 1 and an alkali in a reaction solvent according to a certain ratio, adding acetoxyacetyl chloride in a dropwise manner at a low temperature, and extracting and concentrating after the reaction of the intermediate 1 is finished to obtain an intermediate 2; 3, carrying out a bromination reaction on the intermediate 2 and N-bromosuccinimide, and directlycarrying out water washing extraction to obtain an intermediate 3; 4, carrying out a reaction on the intermediate 3 and excessive piperidine in a solvent, concentrating, extracting with dichloromethane, drying, and further purifying with acetic anhydride to obtain roxatidine acetate; 5, dissolving the intermediate 3 in acetone, adding hydrochloric acid in a dropwise manner to form a salt, filtering, and drying; and 6, mixing with absolute ethyl alcohol, filtering, carrying out cooling crystallization, and drying to obtain the roxatidine acetate hydrochloride.