26650-79-3

Usage

Structure

A derivative of the heterocyclic compound 1,3,5-triazine with a 2,4-dichloro-6-(phenylmethyl) group attached to the triazine ring.

Chemical reactivity

The addition of the 2,4-dichloro-6-(phenylmethyl) group to the triazine ring provides specific chemical reactivity, making it useful in various chemical reactions and applications.

Applications

May be used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds due to its unique chemical structure and reactivity.

Potential medicinal and biological activities

The compound is a subject of interest in pharmaceutical research and development due to its potential medicinal and biological activities.

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 100-39-0 benzyl bromide 

Downstream Products

• 1091629-13-8 C₂₇H₄₇N₇O₂ 
• 1233403-91-2 2-benzyl-4-chloro-6-(morpholin-4-yl)-1,3,5-triazine 

Relevant academic research and scientific papers

Identification and Preclinical Evaluation of the Bicyclic Pyrimidine γ-Secretase Modulator BMS-932481

A triazine hit identified from a screen of the BMS compound collection was optimized for potency, in vivo activity, and off-target profile to produce the bicyclic pyrimidine γ-secretase modulator BMS-932481. The compound showed robust reductions of Aβsub

S-TRIAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME

Novel s-triazine compounds are disclosed and represented by the following: formula (Ia). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, where microbial infection is either a direct cause or a related condition.

Synthesis and biological evaluation of novel 1,3,5-triazine derivatives as antimicrobial agents

Numerous studies have contributed to the development of natural and synthetic antimicrobial peptides as a prospective source of antibiotic agents. Based on the concept that cationic charge, bulk, and lipophilicity are major factors determining antibacterial activity in these peptides, we designed and screened several combinatorial libraries based on 1,3,5-triazine as a template. A set of compounds were identified to show potent antimicrobial activity together with low hemolytic activity.