2669-65-0 Usage
Uses
Used in Pharmaceutical Industry:
MESO-TETRAPHENYLCHLORIN is used as a building block for the development of new pharmaceutical compounds, particularly in the context of drug-delivery systems. Its ability to undergo regioselective reduction allows for the creation of novel molecules with specific properties and functions.
Used in Photodynamic Therapy:
MESO-TETRAPHENYLCHLORIN is used as a photosensitizer for chemo-photodynamic therapy. Its near-UV light absorption property enables it to generate reactive oxygen species upon light activation, which can be employed to target and destroy cancer cells selectively.
Used in Drug Delivery Systems:
To enhance the efficacy and bioavailability of MESO-TETRAPHENYLCHLORIN, it has been explored for use in drug-delivery systems. By incorporating MESO-TETRAPHENYLCHLORIN into various carriers, such as organic and metallic nanoparticles, its delivery to target cells can be improved, leading to better therapeutic outcomes in chemo-photodynamic therapy applications.
Check Digit Verification of cas no
The CAS Registry Mumber 2669-65-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,6 and 9 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2669-65:
(6*2)+(5*6)+(4*6)+(3*9)+(2*6)+(1*5)=110
110 % 10 = 0
So 2669-65-0 is a valid CAS Registry Number.
2669-65-0Relevant academic research and scientific papers
The NMR Spectra of the Porphyrins. 16-Zinc(II) meso-Tetraphenylporphyrin (Zn TPP) as a Diamagnetic Shift Reagent. A Quantitative Ring Current Model
Abraham, Raymond J.,Bedford, Geoffrey R.,McNeillie, David,Wright, Brian
, p. 418 - 425 (2007/10/02)
The facile preparation of zinc(II) meso-tetraphenylporphyrin (Zn TPP) and derivatives from substituted benzaldehydes and pyrrole, combined with the calculation of ring current shifts in these molecules, provides a useful series of selective diamagnetic shift reagents.The porphyrin-ligand equilibrium is examined for some nitrogenous bases and the complexation shifts (ΔP values) are obtained in precisely the same manner as LIS.The parameterization of the double-dipole model of the porphyrin ring current is given, with the inclusion of the phenyl ring currents and free rotation about the substrate-Zn bond.Precise agreement with the porphyrin proton chemical shifts and the complexation shifts of the geometrically rigid substrates of pyridine, 4-picoline and quinuclidine is obtained.In contrast, the 13C complexation shifts in these molecules are subject to additional effects other than the ring current shift.
