267002-55-1

Basic information

• Product Name: Benzenamine, 4-fluoro-2-(2-propenyl)- (9CI)
• Synonyms: Benzenamine, 4-fluoro-2-(2-propenyl)- (9CI)
• CAS NO: 267002-55-1
• Molecular Formula: C₉H₁₀FN
• Molecular Weight: 151.1808032
• Product Categories: HALIDE
• Mol File: 267002-55-1.mol
• Article Data: 25

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenamine, 4-fluoro-2-(2-propenyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-fluoro-2-(2-propenyl)- (9CI)(267002-55-1)
• EPA Substance Registry System: Benzenamine, 4-fluoro-2-(2-propenyl)- (9CI)(267002-55-1)

Safety Data

• Hazardous Substances Data: 267002-55-1(Hazardous Substances Data)

Upstream product

• 83164-79-8 N-allyl-4-fluoroaniline 
• 1089279-33-3 4-fluoro-1-nitro-2-(2-propen-1-yl)benzene 
• 60144-53-8 N-(tert-butoxycarbonyl)-4-fluoroaniline 
• 1361121-46-1 C₁₄H₁₈FNO₂ 
• 371-40-4 4-fluoroaniline 
• 1003-98-1 2-bromo-4-fluoroaniline 
• 24850-33-7 allyltributylstanane 

Downstream Products

• 960208-75-7 N-(2-allyl-4-fluorophenyl)acrylamide 
• 1000848-76-9 N-(2-allyl-4-fluorophenylcarbamoyl)-p-toluenesulfonamide 
• 1361121-51-8 C₉H₁₀FN 
• 1361121-54-1 C₁₆H₁₆FNO₂S 
• 1361121-60-9 C₁₉H₁₈FNO₂S 
• 1374693-99-8 C₂₇H₂₈FNO₆S 
• 1211480-93-1 N,2-diallyl-4-fluoroaniline 
• 1147524-30-8 C₁₆H₁₈FNO 
• 825-70-7 5-fluoro-2-methyl-2,3-dihydro-1H-indole 

Relevant articles and documents

Synthesis of functionalized indoles via palladium-catalyzed cyclization of N-(2-allylphenyl) benzamide: A method for synthesis of indomethacin precursor

We developed an efficient method for synthesis of substituted N-benzoylindole via Pd(II)-catalyzed C-H functionalization of substituted N-(2-allylphenyl)benzamide. The reaction showed a broad substrate scope (including N-acetyl and N-Ts substrates) and substituted indoles were obtained in good to excellent yields. The most distinctive feature of this method lies in the high selectivity for N-benzoylindole over benzoxazine, and this is the first example of Pd(II)-catalyzed synthesis of substituted N-benzoylindole. Notably, this new method was applied for the synthesis of key intermediate of indomethacin.

Green Organocatalytic Synthesis of Indolines and Pyrrolidines from Alkenes

Employing a green and efficient 2,2,2-trifluoroacetophenone-catalyzed oxidation of alkenes, which utilizes H2O2 as the green oxidant, a novel and sustainable synthesis of indolines and pyrrolidines was developed. This constitutes a cheap, general and environmentally-friendly protocol for the synthesis of substituted nitrogen-containing heterocycles. A variety of substitution patterns, both aromatic and aliphatic moieties, are well tolerated leading to the desired nitrogen heterocycles in good to excellent yields. (Figure presented.).

Palladium-Catalyzed Aerobic Intramolecular Aminoacetoxylation of Alkenes Enabled by Catalytic Nitrate

A mild aerobic intramolecular aminoacetoxylation method for the synthesis of pyrrolidine and indoline derivatives was achieved using molecular oxygen as the oxidant. A catalytic NOx species acts as an electron transfer mediator to access a high-valent palladium intermediate as the presumed active oxidant.