960208-75-7Relevant academic research and scientific papers
Palladium(II)-catalyzed oxidative cascade cyclization reactions of anilides and anilines: Scope and mechanistic investigations
Yip, Kai-Tai,Yang, Dan
, p. 2166 - 2175 (2011/10/12)
With Pd(OAc)2/pyridine as the catalyst system and molecular oxygen as a green oxidant, acrylanilides and N-allylanilines undergo oxidative cascade cyclization to form heterocyclic rings in high yields. This methodology is applicable to acrylani
Synthesis of substituted 1-benzazepin-2-ones via ring-closing olefin metathesis
Hoyt, Scott B.,London, Clare,Park, Min
supporting information; experimental part, p. 1911 - 1913 (2009/08/17)
The 1-benzazepin-2-one ring system is an important structural feature of marketed drugs, clinical candidates, and other bioactive molecules. We have developed a new benzazepinone synthesis that employs ring-closing olefin metathesis as a key step. This route provides efficient access to substituted benzazepinones that are difficult to synthesize via existing procedures.
BENZAZEPINONES AS SODIUM CHANNEL BLOCKERS
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, (2008/06/13)
Benzazepinone compounds represented by Formula (I), or pharmaceutically acceptable salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically act
