26770-99-0

Basic information

• Product Name: (1R,3R)-hemicaronic aldehyde
• CAS NO: 26770-99-0
• Molecular Weight: 156.181
• Mol File: 26770-99-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (1R,3R)-hemicaronic aldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3R)-hemicaronic aldehyde(26770-99-0)
• EPA Substance Registry System: (1R,3R)-hemicaronic aldehyde(26770-99-0)

Safety Data

• Hazardous Substances Data: 26770-99-0(Hazardous Substances Data)

Upstream product

• 113323-08-3 (E)-3-[(2S,4S,5R)-4-Methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-acrylic acid methyl ester 
• 27335-35-9 (+/-)-(1R,2S)-2-(methoxycarbonyl)-3,3-dimethyl-1-cyclopropanecarboxylic acid 
• 78984-87-9 methyl 4,5-epoxy-3,3-dimethylpentanoate 
• 62222-77-9 cis-3-hydroxymethyl-2,2-dimethylcyclopropane-1-carboxylic acid lactone 
• 29787-21-1 4-isopropylidene-6,6-dimethyl-3-oxa-bicyclo[3.1.0]hexan-2-one 
• 29787-20-0 3,3,6,6-tetramethylbicyclo[3.1.0]hexane-2,4-dione 
• 713-27-9 (+/-)-2,2-Dimethyl-cis-3-(1-oxo-2-hydroxy-2-methyl-propyl)-cyclopropan-1-carbonsaeure 
• 702-50-1 2,2,5,5-tetramethylcyclohexa-1,3-dione 
• 186581-53-3 diazomethane 
• 26771-21-1 (1R,4R,5S)-4-hydroxy-6,6-dimethyl-3-oxabicyclo[3.1.0]hexa-2-one 
• 76842-28-9 (1R,3S)-3-Chlorocarbonyl-2,2-dimethyl-cyclopropanecarboxylic acid methyl ester 
• 56169-56-3 (1S,3R)-2,2-Dimethyl-3-((1E,3E)-penta-1,3-dienyl)-cyclopropanecarboxylic acid methyl ester 
• 125408-43-7 (1R,3R)-2,2-Dimethyl-3-[(2S,4S,5R)-4-methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-cyclopropanecarboxylic acid methyl ester 
• 7796-72-7 ethyl 3,3-dimethylpent-4-enoate 

Downstream Products

• 1421638-95-0 methyl (1S,3S)-3-[(Z)-2-(4-ethoxyphenyl)ethen-1-yl]-2,2-dimethylcyclopropane-1-carboxylate 
• 1421638-94-9 methyl (1S,3S)-3-[(E)-2-(4-ethoxyphenyl)ethen-1-yl]-2,2-dimethylcyclopropane-1-carboxylate 
• 1421638-93-8 methyl (1S,3S)-3-[(Z)-2-(pentafluorophenyl)ethen-1-yl]-2,2-dimethylcyclopropane-1-carboxylate 
• 1421638-92-7 methyl (1S,3S)-3-[(E)-2-(pentafluorophenyl)ethen-1-yl]-2,2-dimethylcyclopropane-1-carboxylate 
• 1421638-91-6 methyl (1S,3S)-3-[(Z)-2-(2-chlorophenyl)ethen-1-yl]-2,2-dimethylcyclopropane-1-carboxylate 
• 1421638-90-5 methyl (1S,3S)-3-[(E)-2-(2-chlorophenyl)ethen-1-yl]-2,2-dimethylcyclopropane-1-carboxylate 
• 1421638-89-2 methyl (1S,3S)-3-[(Z)-2-(3-methoxyphenyl)ethen-1-yl]-2,2-dimethylcyclopropane-1-carboxylate 
• 1421638-88-1 methyl (1S,3S)-3-[(E)-2-(3-methoxyphenyl)ethen-1-yl]-2,2-dimethylcyclopropane-1-carboxylate 
• 1421638-87-0 methyl (1S,3S)-3-[(Z)-2-(2-methoxyphenyl)ethen-1-yl]-2,2-dimethylcyclopropane-1-carboxylate 
• 1421638-86-9 methyl (1S,3S)-3-[(E)-2-(2-methoxyphenyl)ethen-1-yl]-2,2-dimethylcyclopropane-1-carboxylate 

Relevant articles and documents

Novel synthesis of (d,l) trans-chrysanthemic acid involving a β-diketone fragmentation

Methyl (d,l) trans-chrysanthemate as well as its cis-diastereoisomer have been prepared from dimethyl dimedone, one of their isomers, in a few steps and with complete control of the relative stereochemistry.

ALLYLIC STEREOCENTRE DIRECTED CYCLOPROPANATION. A NEW HIGHLY ENANTIOSELECTIVE SYNTHESIS OF HEMICARONIC ALDEHYDE

isopropyledenetriphenylphosphorane reacts with oxazolidine 4 with excellent ?-face selectivity.The title compound is obtained in high optical purity after removal of the chiral auxiliary.

A SYNTHESIS OF TRANS- AND CIS-CARONALDEHYDES

A preparation of trans- and cis-caronaldehyde derivatives is described by employing iodolactonization reaction as a key step.Investigation is also carried out to establish an asymmetric synthesis by employing the same methodology which allows diastereoselective formation of optically active intermediates in both enantiomeric forms from a single precursor though the degree of asymmetric induction is found to be less satisfactory.