2682-34-0

Basic information

• Product Name: 2-PropynaMide, N,N-diMethyl-
• Synonyms: 2-PropynaMide, N,N-diMethyl-
• CAS NO: 2682-34-0
• Molecular Formula: C₅H₇NO
• Molecular Weight: 97.11518
• Mol File: 2682-34-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 100 °C
• Boiling Point: 113.1±23.0 °C(Predicted)
• Appearance: /
• Density: 0.978±0.06 g/cm3(Predicted)
• PKA: -1.31±0.70(Predicted)
• CAS DataBase Reference: 2-PropynaMide, N,N-diMethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PropynaMide, N,N-diMethyl-(2682-34-0)
• EPA Substance Registry System: 2-PropynaMide, N,N-diMethyl-(2682-34-0)

Safety Data

• Hazardous Substances Data: 2682-34-0(Hazardous Substances Data)

Upstream product

• 2680-03-7 N,N-Dimethylacrylamide 
• 71108-45-7 N, N-dimethyl-2,3-dibromopropionamide 
• 13358-75-3 dimethylcarbamoyl iodide 
• 1111-63-3 potassium acetylide 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 
• 15249-51-1 N,N-dimethylcarbamoyl bromide 
• 1066-26-8 sodium acetylide 
• 124-40-3 dimethyl amine 
• 471-25-0 Propiolic acid 
• 922-67-8 propynoic acid methyl ester 
• 93641-74-8 N,N-dimethyl-3-(trimethylsilyl)propiolamide 

Downstream Products

• 82626-48-0 N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide 
• 1275580-80-7 (η5:κ(P)-diphenylphosphinoethyl-cyclopentadienyl)(3-dimethylamino-3-oxo-prop-1-ynyl)nickel(II) 
• 1275580-51-2 η5-cyclopentadienyl(3-dimethylamino-3-oxo-prop-1-ynyl)(triphenylphosphane)nickel(II) 
• 1416137-08-0 1-benzyl-N,N-dimethyl-1,2,3-triazole-4-carboxamide 
• 1416137-09-1 1-benzyl-N,N-dimethyl-1,2,3-triazole-5-carboxamide 

Relevant articles and documents

Synthesis of 5-aminoisoxazoles from 3-trimethylsilylprop-2-ynamides

Reaction between N,N-disubstituted 3-trimethylsilylprop-2-ynamides and ammonium azide under mild conditions affords hitherto unknown 5-aminoisoxazole derivatives in good yields.

Synthesis method of antineoplastic drug ribociclib intermediate

The invention relates to a synthesis method of an antineoplastic drug ribociclib intermediate. The synthesis method includes the following steps that the electrophilic addition reaction is conducted on N,N-dimethylacrylamide and bromine to obtain N,N-dime

1,1-Diphosphines and divinylphosphines via base catalyzed hydrophosphination

A catalytic hydrophosphination route to 1,1-diphosphines is yet to be reported: these narrow bite angle pro-ligands have been used to great effect as ligands in homogeneous catalysis. We herein demonstrate that terminal alkynes readily undergo double hydrophosphination with HPPh2 and catalytic potassium hexamethyldisilazane (KHMDS) to generate 1,1-diphosphines. A change to H2PPh leads to the formation of P,P-divinyl phosphines.