26825-34-3

Basic information

• Product Name: Benzenamine, 4-chloro-N-(2-pyridinylmethylene)-
• Synonyms: Benzenamine, 4-chloro-N-(2-pyridinylmethylene)-;2-[[(4-Chlorophenyl)imino]methyl]pyridine;4-Chloro-N-(2-pyridinylmethylene)benzenamine;N-(2-Pyridinylmethylene)-4-chloroaniline;N-(2-Pyridylmethylene)-4-chloroaniline;N-(4-Chlorophenyl)-2-pyridylmethyleneamine;N-[(2-Pyridinyl)methylene]-4-chloroaniline
• CAS NO: 26825-34-3
• Molecular Formula: C₁₂H₉ClN₂
• Molecular Weight: 216.67
• Mol File: 26825-34-3.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenamine, 4-chloro-N-(2-pyridinylmethylene)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-chloro-N-(2-pyridinylmethylene)-(26825-34-3)
• EPA Substance Registry System: Benzenamine, 4-chloro-N-(2-pyridinylmethylene)-(26825-34-3)

Safety Data

• Hazardous Substances Data: 26825-34-3(Hazardous Substances Data)

Upstream product

• 100-00-5 4-chlorobenzonitrile 
• 1121-60-4 pyridine-2-carbaldehyde 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 186594-24-1 mer-trichloro(triphenylphosphine oxide)(N-(4-chlorophenyl)-2-pyridinecarboxaldimine)rhenium(III) 
• 868364-31-2 [(η(5)-C5Me5)RhCl(C5H5N-2-CH=NC6H4-p-Cl)BF4 
• 1268280-78-9 [Re(CO)3Br((4-chlorophenyl)pyridin-2-ylmethyleneamine)] 
• 141823-28-1 (((CH₃)2CHC₆H₄CH₃)RuCl(C₅H₄NCHNC₆H₄Cl))⁽¹⁺⁾*ClO₄^(1-)=(((CH₃)2CHC₆H₄CH₃)RuCl(C₅H₄NCHNC₆H₄Cl))(ClO₄) 
• 68090-22-2 1-(4-Chlorphenyl)-5-pyrid-2-yl-1,2,3-triazole 
• 27048-28-8 4-chloro-N-(pyridin-2-ylmethyl)aniline 
• 55643-92-0 2-[3-(4-chloro-phenyl)-4,5-dihydro-3H-[1,2,3]triazol-4-yl]-pyridine 
• 1332757-60-4 diiodobis(N-(4-chlorophenyl)pyridine-2-aldimine)dicopper(I) 

Relevant articles and documents

N,N-Chelate nickel(II) complexes bearing Schiff base ligands as efficient hydrogenation catalysts for amine synthesis

Five N, N-chelate nickel (II) complexes bearing N-(2-pyridinylmethylene)-benzylamine ligands with different substituent groups were synthesized in good yields. The nickel complexes exhibited prominent catalytic efficiency toward amine synthesis from nitro compounds by using NaBH4 or H2 as hydrogen source through two catalytic systems. Various amines with different substituents were obtained in moderate to excellent yields. All substrates with electron-donating and electron-withdrawing properties were tolerated in the two reduction systems. Given the efficient catalytic activity, broad substance scope, and mild reduction conditions, the nickel catalysts have potential applications in industrial production.

Diverse C-6 substituted 4-methyl-2-(2-, 3- and 4-pyridinyl)quinolines: synthesis, in vitro anticancer evaluation and in silico studies

A series of twelve 4-methyl-2-(2-, 3- and 4-pyridinyl)quinolines 7–9 was synthesized using modified Kametani reaction protocol and their in vitro cytotoxicity was tested against human cancer cell lines MCF-7, SKBR-3, PC3, HeLa, comparing with human dermis

Synthesis and evaluation of gold(III) complexes as efficient DNA binders and cytotoxic agents

In recent years, great interest has been focused on gold(III) complexes as cytotoxic and antitumor drugs. Recent studies demonstrated that simple bidentate or polydentate ligands containing nitrogen donor atoms may offer sufficient redox stabilization to produce viable Au(III) anticancer drug targets under physiologic conditions. So, we have synthesized square planer Au(III) complexes of type [Au(An)Clx]Cly and characterized them using UV-Vis absorption, C, H, N elemental analysis, FT-IR, LC-MS, 1H and 13C NMR spectroscopy. These compounds manifested significant cytotoxic properties in vitro for brine shrimp lethality bioassay. The metal complexes were screened for series of DNA binding activity using UV-Vis absorption titration, hydrodynamic measurement and thermal DNA denaturation study. The nucleolytic activity was performed on plasmid pUC19 DNA. The Michaelis-Menten kinetic studies were performed to evaluate rate of enhancement in metal complexes mediated DNA cleavage over the non-catalyzed DNA cleavage.