268556-75-8Relevant academic research and scientific papers
Enantioselective organocatalysis of Strecker and Mannich reactions based on carbohydrates
Becker, Christian,Hoben, Christine,Kunz, Horst
, p. 417 - 424 (2008/02/07)
Efficient organocatalysts for enantioselective Strecker and Mannich reactions were constructed from glucosamine as a readily accessible chiral scaffold. A variety of aromatic aldimines were subjected to hydrocyanation with good to excellent yield (72-98%)
Enantioselective catalytic addition of HCN to ketoimines. Catalytic synthesis of quaternary amino acids.
Vachal,Jacobsen
, p. 867 - 870 (2007/10/03)
[formula: see text] Highly enantioselective addition of HCN to ketoimines has been achieved for the first time using readily accessible and recyclable Schiff base catalysts. Essentially quantitative isolated yield and enantioselectivity of up to 95% ee wa
