26891-64-5Relevant articles and documents
Terminal pyridine-N ligation at [FeFe] hydrogenase active-site mimic
Zhang, Yue,Hu, Ming-Qiang,Wen, Hui-Min,Si, You-Tao,Ma, Cheng-Bing,Chen, Chang-Neng,Liu, Qiu-Tian
, p. 2576 - 2580 (2009)
Diiron model complexes (μ-pdt)Fe2(CO)5L with L = pyridine ligands, e.g. py (A), etpy (B), btpy (C), were synthesized as active site analogues of [FeFe] hydrogenase, and characterized by X-ray crystallography and electrochemistry. Pyr
Nucleophilic Displacement of Primary Amino Groups via 1-Substituted 4-Tosylimidazoles
Taylor, Edward C.,LaMattina, John L.,Tseng, Chi-Ping
, p. 2043 - 2047 (2007/10/02)
Two methods are discribed for the replacement of primary amino groups, situated either α or γ to a heterocyclic nitrogen atom, by ethoxy, alkylthio, and arylthio substituents, by Wittig reagents, and by hydrogen.Both methods involve transformation of the primary amino group into a nucleofugic pendant heterocycle.The first converts the primary amino group into a 5-phenyl-1-tetrazolyl substituent by benzoylation, formation of the imidoyl chloride, and reaction with sodium azide, while the second converts the primary amino group into a 1-(4-tosylimidazolyl) substituent by reaction with triethyl orthoformate and acid to give the (ethoxymethylene)amino derivative, which is then condensed with tosylmethyl isocyanide (TosMIC) anion.The 1-(4-tosylimidazolyl) substituent is shown to be more susceptible to nucleophilic displacement by a wider range of nucleophiles.
