26905-40-8

Usage

Uses

3-Methoxybenzylmagnesium chloride is used as pharmaceutical intermediate.

InChI:InChI=1/C8H9O.ClH.Mg/c1-7-4-3-5-8(6-7)9-2;;/h3-6H,1H2,2H3;1H;/q-1;;+2/p-1

Upstream product

• 824-98-6 m-methoxybenzyl chloride 
• 7789-45-9 copper(II)bromide 

Downstream Products

• 54100-19-5 1-Methoxy-3-((3E,7E)-4,7,8-trimethyl-dodeca-3,7,11-trienyl)-benzene 
• 6266-57-5 1,2-bis(3-methoxyphenyl)ethan-1-one 
• 98006-19-0 (3aS,7aR)-4-[2-(3-Methoxy-phenyl)-eth-(E)-ylidene]-7a-methyl-1-methylene-1,2,3,3a,4,7a-hexahydro-inden-5-one 
• 134272-35-8 (4R,5S)-N-benzyl-5-(tert-butyldimethylsilyl)oxy-4-(3-methoxyphenyl)methyl-2-pyrrolidinone 
• 80704-91-2 (3R,4R)-3,4-bis<(3-methoxyphenyl)methyl>dihydro-2(3H)-furanone 
• 30431-10-8 (4aR,4bR,8S,8aR,10aR)-8-[2-(3-Methoxy-phenyl)-ethyl]-1,1,4a,8,8a-pentamethyl-dodecahydro-phenanthrene-2,7-dione 
• 66325-64-2 3'-methoxybenzylcyclohexanol 
• 791096-42-9 (1S,4S)-4-(3-Methoxy-benzyl)-cyclopent-2-enol 
• 891833-63-9 2,2-dimethyl-propionic acid 4,5-bis-(2,2-dimethyl-propionyloxy)-6-(2,2-dimethyl-propionyloxymethyl)-2-[4-(3-methoxy-benzyl)-2-oxo-3,4-dihydro-2H-pyridin-1-yl]-tetrahydro-pyran-3-yl ester 
• 171230-53-8 (4S)-[(3-methoxyphenyl)methyl]dihydro-2(3H)-furanone 
• 185254-91-5 (3S,4S)-3,4-bis[(3-methoxyphenyl)methyl]dihydro-2(3H)-furanone 
• 791096-46-3 (S)-4-(3-Methoxy-benzyl)-tetrahydro-furan-2-ol 
• 791096-43-0 tert-Butyl-[(1S,4S)-4-(3-methoxy-benzyl)-cyclopent-2-enyloxy]-dimethyl-silane 

Relevant academic research and scientific papers

4,5-diaryloxazole derivatives

Heterocyclic compounds of the formula: whereinR1 is carboxy or protected carboxy, R2 is aryl which may have suitable substituent(s), R3 is aryl which may have suitable substituent(s), A1 is lower alkylene, A2 is bond or lower alkylene and -Q- is etc., and pharmaceutically acceptable salts thereof which are useful as a medicament.

CYCLISATION DE DIARYLALCANES EN MILIEU SUPERACIDE: SYNTHESE DE CETONES TRICYCLIQUES A METHYLE ANGULAIRE ET MECANISME DE LEUR ISOMERISATION

Cyclisation of redily available diaryl-1,2 ethanes 1-4 proceeds in SbF5-HF at 0oC to yield tricyclic phenantrenones 5,6,7 and 11 bearing an angular methyl group.This process implies the electrophilic attack of the more basic aromatic ring, reacting through its disprotonated form (on the oxygen and the meta carbon atom) on the second aromatic ring.Isomerization of these primary products may be observed (to give ketones 8,9,10 from 3 and 12 from 4) and it has been demonstrated by the use of specifically deuterated 3d that it involves stereospecific 1,2 hydride (or deuteride) shifts, without exchange.