26928-10-9

Upstream product

• 1038923-52-2 1-triethylsiloxy-2,3,3-trifluoro-1-(4-tolyl)prop-2-ene 
• 1427-33-4 1,1,2-trifluoro-2-trimethylsilylethylene 
• 104-87-0 4-methyl-benzaldehyde 
• 680-76-2 triethyl(trifluorovinyl)silane 
• 1198794-75-0 C₁₀H₉ClF₄O 
• 2356-16-3 ethyl(diethylphosphono)(fluoro)acetate 
• 124-38-9 carbon dioxide 
• 28321-07-5 1-(2,2-difluorovinyl)-4-methylbenzene 

Downstream Products

• 120681-12-1 (Z)-2-Fluoro-3-p-tolyl-acryloyl chloride 
• 120710-91-0 N-(α-fluoro-4-methylcinnamoyl)-L-phenylalanine 
• 109833-25-2 2-((Z)-2-Fluoro-3-p-tolyl-acryloylamino)-3-phenyl-propionic acid 

Relevant academic research and scientific papers

A novel reaction of β,β'-dihydroxy acids or esters with vanadium(V) trichloride oxide. New entry to the stereoselective synthesis of α-fluoro- α,β-unsaturated acids and esters

β,β'-Dihydroxy carboxylic acids and esters, readily prepared from dibromofluoroacetate and aldehydes, underwent deoxygenation, followed by elimination of aldehyde by the action of vanadium(V) trichloride oxide at the reflux temperature of chlorobenzene fo

Fluorine-containing carboxylic acid compound and preparation method thereof

The invention provides a fluorine-containing carboxylic acid compound and a preparation method and application thereof. The preparation method comprises the steps that a fluorine-containing olefin compound and CO2 react in a solvent in the presence of a c

Copper-Catalyzed Carboxylation of C-F Bonds with CO2

An effective Cu-catalyzed selective formal carboxylation of C-F bonds with an atmospheric pressure of CO2 is reported. A variety of gem-difluoroalkenes, gem-difluorodienes, and α-trifluoro-methyl alkenes show high reactivity and selectivity for

An efficient synthesis of (Z)-α-fluorochalcones via the palladium-catalyzed cross-coupling reaction of (Z)-α-fluorocinnamoyl chloride with boronic acids

An efficient synthesis of α-fluorochalcones (1,3-diphenyl-2- fluoroprop-2-en-1-one) based on the Suzuki-Miyaura palladium-catalyzed cross-coupling reaction of arylboronic acids with α-fluorocinnamoyl chlorides in the presence of Cs2CO3/su

Synthetic utilization of 2-chloro-1,1,1,2-tetrafluoroethane

β-Substituted α-fluoro-α,β-unsaturated carboxylic acids have been successfully synthesized, usually in a (Z)-stereospecific manner by way of a stepwise or a one-pot three-step procedure starting from 2-chloro-1,1,1,2-tetrafluoroethane (HCFC-124), one of the major byproducts of the industrial process for tetrafluoroethene formation from chlorofluoromethane (HCFC-22). Get some Z's! β-Substituted α-fluoro-α,β- unsaturated carboxylic acids have been successfully synthesized from 2-chloro-1,1,1,2-tetrafluoroethane, one of the major byproducts of tetrafluoroethene formation from chlorofluoromethane. The products are usually obtained with Z stereoselectivity, by either a stepwise or a one-pot three-step procedure (see scheme).

Insight into the reactions of trifluorovinylsilanes with aromatic aldehydes

The conditions for the selective addition of trialkyl(trifluorovinyl) silanes to the C=O bond of aromatic aldehydes in the presence of cesium fluoride to give the corresponding "silylated" alcohols in high yields was performed. The reactivity of the "sily