26931-99-7

Upstream product

• 126705-57-5 3-(3'-hydroxyisopentyl)-4-methoxy-methoxyacetophenone 
• 79324-77-9 1‐(3‐iodo‐4‐methoxyphenyl)ethan‐1‐one 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 126705-61-1 4-<5'-(1'-hydroxyethyl)-2-methoxyphenyl>-2-methyl-butan-2-ol 
• 126705-58-6 methyl 3-<5'-(1''-hydroxyethyl)-2'-methoxyphenyl>propanoate 
• 126705-59-7 methyl 3-(5'-acetyl-2'-methoxyphenyl)propanoate 
• 99-93-4 4-Hydroxyacetophenone 
• 503-60-6 3,3-dimethyl-allyl chloride 
• 26932-05-8 1-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]ethanone 
• 74-88-4 methyl iodide 
• 157953-19-0 1-[3-(3-Hydroxy-3-methyl-but-1-ynyl)-4-methoxy-phenyl]-ethanone 

Relevant academic research and scientific papers

Design, synthesis, and evaluation of bromo-retrochalcone derivatives as protein tyrosine phosphatase 1B inhibitors

A series of bromo-retrochalcones was designed, synthesized and evaluated as PTP1B inhibitors based on licochalcone A and E. Compounds 6, 12, 13, 14, 25, 36, 37, 39, and 41 showed potent inhibitory effects against PTP1B, and compound 37, the most potent am

REGIOSELECTIVE PRENYLATION OF PHENOLS BY PALLADIUM CATALYST: SYNTHESES OF PRENYLPHENOLS AND CHROMANS

The palladium-catalyzed coupling reaction of iodophenols (1) with 2-methyl-3-butyn-2-ol gave alkynylphenols (2).Catalytic hydrogenation of 2 over Raney nickel and the subsequent dehydration of the resultant alkylphenols (3) gave regioselectively the desired prenylphenols (4).Dehydration of alkylphenols (3f-h) gave chromans (7).

Synthesis of two meroterpenic acetophenones occurring in Senecia and Helianthella species

Starting from the common synthon, methyl 3-propanoate (4), the syntheses of two naturally occurring meroterpenes, 4-hydroxy-3-(3'-hydroxyisopentyl)acetophenone (1) and 3-(2-isopenten-1-yl)-4-methoxyacetophenone (3)