269410-04-0

Basic information

• Product Name: 2,4,6-TriMethoxyphenylboronic acid, pinacol ester
• Synonyms: 2,4,6-TriMethoxyphenylboronic acid, pinacol ester;4,4,5,5-tetramethyl-2-(2,4,6-trimethoxyphenyl)-1,3,2-dioxaborolane
• CAS NO: 269410-04-0
• Molecular Formula: C₁₅H₂₃BO₅
• Molecular Weight: 312.1664
• Mol File: 269410-04-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4,6-TriMethoxyphenylboronic acid, pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-TriMethoxyphenylboronic acid, pinacol ester(269410-04-0)
• EPA Substance Registry System: 2,4,6-TriMethoxyphenylboronic acid, pinacol ester(269410-04-0)

Safety Data

• Hazardous Substances Data: 269410-04-0(Hazardous Substances Data)

Usage

General Description

2,4,6-TriMethoxyphenylboronic acid, pinacol ester is a chemical compound with the molecular formula C18H24B2O6. It is a boronic acid derivative that is commonly used in organic synthesis as a reagent for Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds. 2,4,6-TriMethoxyphenylboronic acid, pinacol ester has three methoxy groups and a pinacol moiety attached to the boronic acid group, making it a versatile and effective reagent for the construction of complex organic molecules. It is a white to off-white powder that is stable under normal conditions and has a variety of applications in the field of organic chemistry.

Upstream product

• 67827-56-9 2,4,6-trimethoxychlorobenzene 
• 73183-34-3 bis(pinacol)diborane 
• 1131-40-4 2-bromo-1,3,5-trimethoxybenzene 
• 621-23-8 1,2,3-trimethoxybenzene 
• 2510-49-8 2-iodo-1,3,5-trimethoxybenzene 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 

Relevant articles and documents

Economical and Readily Accessible Preparation of o,o-Disubstituted Arylboronates through Palladium-Catalyzed Borylation of Haloarenes

Miyaura borylation, that is, palladium-catalyzed cross-coupling between bromoarenes and diboron, offers a versatile method for preparing arylboronates; however, a costly and inaccessible catalyst has been required for synthesizing highly congested arylboronates with the method. Here the Pd(OAc)2–tri(4-methoxyphenyl)phosphine catalyst was found to work as an efficient catalyst for the sterically demanding borylation. A broad range of o,o-disubstituted bromoarenes were converted into the corresponding arylboronates in high yields by using the palladium catalyst with Cs2CO3 in EtOAc at 80 °C.

Double N,B-Type Bidentate Boryl Ligands Enabling a Highly Active Iridium Catalyst for C-H Borylation

Boryl ligands hold promise in catalysis due to their very high electron-donating property. In this communication double N,B-type boryl anions were designed as bidentate ligands to promote an sp2 C-H borylation reaction. A symmetric pyridine-con

Nano-Fe2O3-catalyzed direct borylation of arenes

Nano-Fe2O3-catalyzed borylation of arenes with diboron pinacol ester B2pin2 has been found to give borylation products with selectivity controlled by electronic effects of substituents. The Royal Society of Chem