26964-94-3

Upstream product

• 109925-93-1 5,5-Dimethyl-3-phenyl-6-trimethylsiloxy-5,6-dihydro-4H-1,2-oxazin 
• 2403-57-8 1-(2-methylprop-1-en-1-yl)pyrrolidine 
• 14181-72-7 2-bromo-1-phenyl-ethanone oxime 

Downstream Products

• 26965-05-9 4-Hydroxy-3,3-dimethyl-1-phenyl-butan-1-one oxime 

Relevant academic research and scientific papers

Transition Metal- and Acid-Induced Transformations of 6-Siloxy-Substituted 5,6-Dihydro-4H-1,2-oxazines: Preparation of Pyrroles, Nitrones, 1,4-Dicarbonyl Compounds and Derivatives Thereof

A variety of 6-siloxy-substituted 5,6-dihydro-4H-1,2-oxazines (abbreviation: 1,2-oxazines) 1, 3 could be transformed into di- and trisubstituted pyrroles 2, 4 by means of molybdenum hexacarbonyl.The mechanism of this deoxygenating ring contraction is discussed.With two bicyclic 1,2-oxazines an acid-catalyzed fragmentation affording α-methylenecycloalkanones 7 has been observed, while other 1,2-oxazines rearrange in methanolic acid to give nitrones 9, 10.The desilylation of 6-siloxy-substituted 1,2-oxazines 1.3 employing NEt3*3HF is a very general and smooth process providing 6-hydroxy-1,2-oxazines 11, 12 or their corresponding acyclic tautomers 13, 14 in high yields.For two examples of 11 deoximations by use of formalin could be achieved with moderate efficiency giving 1,4-dicarbonyl compounds 15.