14181-72-7

Basic information

• Product Name: 2-BROMO-1-PHENYL-1-ETHANONE OXIME
• Synonyms: 2-BROMO-1-PHENYL-1-ETHANONE OXIME;2-BroMo-1-phenylethanone oxiMe
• CAS NO: 14181-72-7
• Molecular Formula: C₈H₈BrNO
• Molecular Weight: 214.06
• Mol File: 14181-72-7.mol

Chemical Properties

• Melting Point: 97-100
• Boiling Point: 296.8°Cat760mmHg
• Flash Point: 133.3°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 0.00063mmHg at 25°C
• Refractive Index: 1.57
• CAS DataBase Reference: 2-BROMO-1-PHENYL-1-ETHANONE OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-1-PHENYL-1-ETHANONE OXIME(14181-72-7)
• EPA Substance Registry System: 2-BROMO-1-PHENYL-1-ETHANONE OXIME(14181-72-7)

Safety Data

• Hazard Codes: C
• Statements: R34:Causes burns.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl
• Hazardous Substances Data: 14181-72-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H8BrNO/c9-6-8(10-11)7-4-2-1-3-5-7/h1-5,11H,6H2/b10-8+

Upstream product

• 98-86-2 acetophenone 
• 546-88-3 acetylhydroxamic acid 
• 70-11-1 α-bromoacetophenone 
• 2142-69-0 2-bromophenyl methyl ketone 

Downstream Products

• 29441-75-6 6-methyl-8a-morpholin-4-yl-3-phenyl-4a,5,6,7,8,8a-hexahydro-4H-benzo[e][1,2]oxazine 
• 29441-70-1 9a-morpholin-4-yl-3-phenyl-4,4a,5,6,7,8,9,9a-octahydro-cyclohepta[e][1,2]oxazine 
• 79379-53-6 5-Ethyl-6-morpholin-4-yl-3-phenyl-5,6-dihydro-4H-[1,2]oxazine 
• 107182-86-5 (Z)-α-(1,2,3,4-Tetrahydro-2-isochinolyl)-acetophenonoxim 
• 16451-77-7 (E)-α-(1,2,3,4-Tetrahydro-2-isochinolyl)-acetophenonoxim 
• 132868-23-6 3,6-Diphenyl-6-trimethylsilanyloxy-5,6-dihydro-4H-[1,2]oxazine 
• 79379-49-0 2-Phenyl-1,4,5,6,7,8-hexahydro-cyclohepta[b]pyrrole 
• 100181-16-6 6,6-Bis-(4-methoxy-phenyl)-3-phenyl-4H-[1,5,2]oxathiazine 
• 4057-62-9 3-phenyl-1,2,5-thiadiazole 
• 151133-39-0 3-Bromo-4-phenyl-[1,2,5]thiadiazole 
• 104942-45-2 4-phenyl-3-hydroxythiazole-2(3H)-thione 
• 79379-48-9 4,5-dihydro-2-phenylcyclopentapyrrole 
• 16206-34-1 3‐methyl‐2,5‐diphenyl‐1H‐pyrrole 
• 79379-50-3 4-Ethyl-2-phenyl-1H-pyrrole 

Relevant articles and documents

α-Nitrosostyrenes as Three-Atom Units for the (3+1) Cyclization Reaction: Facile Access to 2,3-Dihydrodiazete N-Oxides and Their Diversified Synthetic Conversions

An unprecedented (3+1) cyclization of α-nitrosostyrenes, generated in situ from α-bromooximes, and N-tosyloxycarbamates was developed, which enables the synthesis of a range of structurally unique and hitherto unexplored 2,3-dihydrodiazete N-oxides in mod

Copper-Catalyzed Annulation of Oxime Acetates with α-Amino Acid Ester Derivatives: Synthesis of 3-Sulfonamido/Imino 4-Pyrrolin-2-ones

A copper-catalyzed annulation of oxime acetates and α-amino acid ester derivatives for the easy preparation of 4-pyrrolin-2-ones bearing a 3-amino group has been developed. This process features the oxidation of amines with oxime esters as the internal oxidant to produce the active 1,3-dinucleophilic and 1,2-dielectrophilic species concurrently. The subsequent nucleophilic cyclization realizes the efficient construction of 4-pyrrolin-2-one derivatives.

An efficient synthesis of 2-isoxazolines from α-haloketone oximes and dimethyl sulfonium salts

2-Isoxazolines were synthesized efficiently from a formal [4+1] cycloaddition of nitrosoalkenes and sulfur ylides, which were generated in situ from α-haloketone oximes and dimethyl sulfonium salts. This approach provides a new method to synthesize a rang

A DEVELOPING AGENT PRECURSOR FOR LASER MARKABLE COMPOSITIONS

The invention relates to novel laser markable compositions comprising developing agent precursors according to formula (I).

Synthesis and Beckmann rearrangement of novel (Z)-2-organylselanyl ketoximes: promising agents against grapevine anthracnose infection

We present here the synthesis of novel (Z)-2-organylselanyl ketoximes by nucleophilic substitution reaction of E/Z mixtures of 2-bromo ketoximes with nucleophilic species of selenium, which were generated in situ by simple cleavage of diorganyl diselenides with NaBH4using ethanol/THF as solvent. The new 2-organylselanyl ketoximes were synthesized in moderate to good yields and with selectivity for the (Z)-configuration. The synthesized (Z)-2-arylselanylacetophenone oximes were submitted to the Beckmann rearrangement, furnishing the corresponding N-aryl-2-(selanyl)acetamides. (Z)-1-Phenyl-2-(phenylselanyl) ketoxime has antifungal activity against Sphaceloma ampelinum and a good level of antioxidant activity in vitro in DPPH, ABTS, FRAP and lipid peroxidation assays.

Nitrimines as reagents for metal-free formal C(sp2)-C(sp2) cross-coupling reactions

Nitrimines are employed as powerful reagents for metal-free formal C(sp2)-C(sp2) cross-coupling reactions. The new chemical process is tolerant of a wide array of nitrimine and heterocyclic coupling partners giving rise to the corresponding di- or trisubstituted alkenes, typically in high yield and with high stereoselectivity. This method is ideal for the metal-free construction of heterocycle-containing drug targets, such as phenprocoumon.

Europium(III) triflate-catalyzed Trofimov synthesis of polyfunctionalized pyrroles

The synthesis of polyfunctionalized pyrroles by reaction of a ketoxime with dimethyl acetylenedicarboxylate using europium(III) triflate as the catalyst is described. Copyright

Cycloaddition of nitrones with arynes generated from benzobisoxadisilole or 2,3-naphthoxadisilole

1,3-Dipolar cycloaddition of nitrones with arynes generated in situ from benzobisoxadisilole or 2,3-naphthoxadisilole afforded the oxadisilole fused benzo[d]isoxazoline or the naphtho[2,3-d]isoxazoline derivatives at room temperature in good yields.

Unprecedented formation of Δ2-isoxazoline and/or 1-nitroso-pyrazoline from α-bromoketone oximes and diazo compounds

Reaction of α-bromoketone oximes with diazo compounds in the presence of a metal catalyst and base led to the unprecedented formation of two types of rings: Δ2-isoxazolines and 1-nitrosopyrazolines.

Hetero-Diels-Alder reaction of [60]fullerene with nitrosoalkene

A new type of stable C60-fused dihydrooxazine derivatives was successfully prepared by the hetero-Diels-Alder reaction of C60 with nitrosoalkene generated in situ by extrusion of HBr from the corresponding α-bromooxime.