26965-47-9Relevant academic research and scientific papers
Convenient synthesis of some 3-phenyl-1-benzofuran-2-carboxylic acid derivatives as new potential inhibitors of ClC-Kb channels
Piemontese, Luca,Carbonara, Giuseppe,Fracchiolla, Giuseppe,Laghezza, Antonio,Tortorella, Paolo,Loiodice, Fulvio
experimental part, p. 2865 - 2872 (2011/04/24)
Improved experimental conditions were carried out for the preparation in high yields of some 3-phenyl-1-benzofuran-2-carboxylic acids, potent inhibitors of ClC-K chloride channels. A one-pot condensation-cyclization was set up starting from different 2-hy
Condensed heterocyclic compounds useful for inhibiting acyl-CoA
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, (2008/06/13)
Novel compound represented by the formula: STR1 wherein ring A, ring B and ring C each stands for an optionally substituted benzene ring; X stands for --NR-- wherein R stands for hydrogen atom or an optionally substituted hydrocarbon group, --O-- or --S--; Y stands for --(CH2)n-- wherein n denotes 1 or 2 or --NH--; and Ra stands for a hydrogen atom or an optionally substituted hydrocarbon group, provided that when ring C is unsubstituted or substituted only at para-position, ring B is substituted at least at ortho-position or a salt thereof which have an excellent acyl-CoA: cholesterol acyltransferase inhibiting action and cholesterol-lowering activity, their production and medicinal use.
Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
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, (2008/06/13)
A compound of the formula : wherein R1 isaryl which may be substituted with halogen, nitro, amino, lower alkylamino, lower alkoxy or acylamino, R2 ishydrogen; alkyl; cycloalkyl; or lower alkyl which is substituted with cyclo(lower)alkyl, cyclo(lower)alken
