270076-02-3Relevant academic research and scientific papers
Chemoenzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-d-erythritol: a substrate for IspE
Narayanasamy, Prabagaran,Eoh, Hyungjin,Crick, Dean C.
, p. 4461 - 4463 (2008)
Enantiomerically pure 2-C-methyl-d-erythritol 4-phosphate 1 (MEP) is synthesized from 1,2-O-isopropylidene-α-d-xylofuranose via facile benzylation in good yield. Subsequently, 1 is used for enzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-d-erythritol
Synthesis of simple adenosine diphosphate ribose analogues
Chevallier, Olivier P.,Migaud, Marie E.
, p. 1127 - 1143 (2008/12/23)
(Chemical Equation Presented) The synthesis of analogues of adenosine diphosphate ribose and acetylated adenosine diphosphate ribose, modified at the northern pentose, is reported. The stereochemistry at the acetylated centers was chosen to minimize acety
Chemical synthesis of enantiopure 2-C-methyl-D-erythritol 4-phosphate, the key intermediate in the mevalonate-independent pathway for isoprenoid biosynthesis
Hoeffler, Jean-Fran?ois,Pale-Grosdemange,Rohmer, Michel
, p. 1485 - 1489 (2007/10/03)
Optically pure 2-C-methyl-D-erythritol 4-phosphate, a key intermediate in the mevalonate-independent route for isoprenoid biosynthesis, is conveniently synthesized from 1,2-O-isopropylidene-α-D-xylofuranose, including the possibility of radiolabeling of t
