270076-07-8

Upstream product

• 270076-05-6 3-O-benzyl-1,2-O-isopropylidene-3-C-methyl-α-D-ribofuranose 5-dibenzylphosphate 
• 270076-02-3 5-O-dibenzylphosphono-1,2-O,O-isopropylidene-α-D-xylofuranose 
• 270076-04-5 1,2-O-isopropylidene-3-C-methyl-α-D-ribofuranose 5-dibenzylphosphate 
• 270076-03-4 1,2-O-isopropylidene-α-D-erythro-pentofuranose-3-ulose 5-dibenzylphosphate 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 538-37-4 dibenzyl phosphochloridate 

Downstream Products

• 270076-08-9 2-O-benzyl-2-C-methyl-D-erythritol 4-dibenzylphosphate 

Relevant academic research and scientific papers

Chemoenzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-d-erythritol: a substrate for IspE

Enantiomerically pure 2-C-methyl-d-erythritol 4-phosphate 1 (MEP) is synthesized from 1,2-O-isopropylidene-α-d-xylofuranose via facile benzylation in good yield. Subsequently, 1 is used for enzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-d-erythritol

Chemical synthesis of enantiopure 2-C-methyl-D-erythritol 4-phosphate, the key intermediate in the mevalonate-independent pathway for isoprenoid biosynthesis

Optically pure 2-C-methyl-D-erythritol 4-phosphate, a key intermediate in the mevalonate-independent route for isoprenoid biosynthesis, is conveniently synthesized from 1,2-O-isopropylidene-α-D-xylofuranose, including the possibility of radiolabeling of t